Biochemistry and Cell Biology

Faculty	Research Area(s)
Carolyn Adler	Stem cell biology in planarian flatworms; organ regeneration; transcriptional and cell biological responses to tissue injuries; animal behavior - lab
Hector Aguilar-Carreno	Entry, egress, and interactions of enveloped viruses with host cells, with emphasis on emerging paramyxoviruses, vaccine and antiviral strategies -  lab
Nicolas Buchon	Host/microbe relationships and control of intestinal stem cell behavior in homeostasis and disease - lab
Soon Hon Cheong	Cellular and molecular medicine; developmental and reproductive biology; infectious diseases; population medicine and epidemiology; structural and functional biology - lab
Paula E. Cohen	Etiology of spontaneous birth defects in mammals; mechanisms of meiotic recombination; DNA repair proteins in meiosis and recombination; germ cell development; ovarian development - lab
Ruth Collins	Pharmacology; cancer cell biology; small GTPase regulation of intracellular traffic and cellular growth control - lab
Brian Crane	Protein redox chemistry; electron-transfer reactions; mechanisms of signal transduction; circadian clocks; protein photosensors; bacterial chemotaxis; receptor signaling; nitric oxide enzymology; metallobiochemistry - lab
Susan Daniel	Dr. Daniel leads a research group of biomolecular engineers working to understand cell membrane functions and the biological processes that happen within them. Her group pioneered the use of “cell-free” biomembrane platforms for re-creating cellular processes on chip. Much of the work they do has impact in human health or advancing biotechnologies for the good of humankind.
Robin Dando	Taste and sensory science, the biology of how we perceive foods, obesity and metabolic diseases – lab
Charles Danko	Medical genetics and genomics and cancer biology research
Arunika Das	Genetic and epigenetic mechanisms of chromosome inheritance and aging during meiosis and early development.
Michelle Delco	Investigating mitochondria as a link between cartilage trauma and osteoarthritis to understand how joint injury leads to arthritis in horses and humans
Matthew DeLisa	Molecular biotechnology; protein biogenesis and folding pathways; protein engineering - lab
Tobias Doerr	Cell envelope biology of Gram-negative pathogens; antibiotic resistance; tolerance and mechanism of action; microbial stress responses - lab
Maria Julia Bevilaqua Felippe	Cellular and molecular mechanisms involved in B cell response; neonatal immunology and response to vaccination; immunomodulation using biologic response modifiers; cancer immunotherapy; characterization of primary and secondary immunodeficiencies - lab
Andrew Flyak	human antibody response to viral pathogens; use immunologic and biochemistry assays and use structural biology techniques to “see” how antibodies bind and neutralize viral pathogens - Lab
Chun Han	mechanisms of dendrite morphogenesis and neurodegeneration using Drosophila sensory neurons as a model system - lab
Gunther Hollopeter	Molecular mechanisms of membrane trafficking in multicellular systems, in vivo imaging and CRISPR/Cas9 genome engineering in C. elegans, protein biochemistry and structural biology of clathrin adaptor complexes - lab
Fenghua Hu	Molecular and cellular mechanisms of neurodegeneration - lab
Kelly Hume	Cancer biology; veterinary oncology; clinical oncology; molecular oncology; DNA damage; chemosensitivity and novel therapeutics
Saki Ichikawa	My group integrates chemical biology, organic chemistry, and chemical proteomics to explore the intricacies of protein modifications and their impacts on biological systems - lab
Jongmin Kim	Gene silencing in germ cells. - chromatin structure and transcriptional fidelity in spermatogenesis.
Elizabeth Johnson	bioactive lipids shape host-microbe interactions; host-microbe molecule exchange and bioactive lipids in infant nutrition
Toshi Kawate	Structures and mechanisms of membrane proteins that regulate extracellular signaling - lab
Satoshi Kimura	Kimura lab focuses on translation mechanisms in bacterial pathogens.
Gary Koretzky	Aims to better understand the signal transduction events that occur following engagement of the T cell antigen receptor; study more globally the molecular events important for immune cell development, differentiation and function
Natasza Kurpios	Tissue morphogenesis; cell shape and architecture; organ development; gut morphogenesis; mammary gland biology; breast cancer - lab
Jan Lammerding	Cellular biomechanics; mechanotransduction; cell migration; muscular dystrophy and cancer cell biology - lab
Esak Lee	The laboratory is currently focused on further advancing the novel 3D organ-on-chip systems, as well as developing both cellular and molecular tools and in vivo models, to better understand the mechanisms through which cells regulate their response to biological and mechanical cues - lab
Cynthia Leifer	Understanding innate immunity from the receptors that detect microbes to how innate immune cells react to changes in their environment during inflammatory processes - lab
Karl Lewis	we interrogate how the acute sensing mechanisms in musculoskeletal cells relate to tissue level changes in healthy and disease states - lab
David Lin	Axon guidance; neurodevelopment; epilepsy; autism; genomics - lab
Maurine Linder	Regulation of cell signaling by protein lipidation
Sabine Mann	Metabolic diseases and insulin signaling; nutrition; epidemiology; metabolic and nutritional immunology
Eirene Markenscoff-Papadimitriou	gene-regulatory mechanisms that generate diversity during brain development; probe function of human genetic variants linked to autism - lab
Katharyn Mitchell	Large Animal Internal Medicine
Zeribe Nwosu	Cancer metabolism and therapeutic opportunities
Joseph Peters	We are generally interested in genomic stability and chromosome evolution, especially how these are impacted by mobile DNA elements.  We have a special interest in molecular mechanisms mobile elements capable of moving between positions in the genome called transposons use to limit damage to the host and maximize the process of horizontal transfer.
Shu-Bing Qian	Translational control of gene expression; signaling pathways in stress response; protein quality control in metabolic diseases - lab
Richa Sardana	Membrane protein trafficking and quality control mechanisms - lab
Luis Schang	Role of cellular protein, lipids, and glycans play in viral infection
Carolyn Sevier	Signaling of cellular oxidative stress; molecular mechanisms used by cellular pathways that sense and signal redox imbalances within the cell
Marcus Smolka	Cell signaling and genome maintenance; DNA replication stress; Phosphoproteomics
Jeongmin Song	Bacterial toxins; Salmonella Typhi; bacterial pathogenesis - lab
 Ayshwarya Subramanian	Dr. Subramanian’s research focuses on understanding the principles governing cellular heterogeneity, crosstalk, and evolution in the context of human tissues and disease. Her interdisciplinary research program operates at the nexus of high-throughput data measurements, development and application of computational methods, and experimental design, with key collaborations for clinical samples, and mechanistic validations in vivo and in situ.
Alexander J. Travis	Comparative biology of male germ cells; signaling and metabolism of sperm during capacitation; organization of lipid raft membrane sub-domains in sperm; applications of technologies using reproductive stem cells for wildlife conservation - lab
Meng Wang	We use molecular biology, genetics and animal models to dissect how our metabolism gives rise to chemicals that damage our DNA- Wang Lab
Robert Weiss	Molecular mechanisms for the maintenance of genomic stability; cellular responses to DNA damage; mouse models of human cancer - lab
Andrew C. White	Cancer biology; stem cell biology; biochemistry and cell biology - lab
Gary R. Whittaker	Role of nuclear import and export in influenza virus infection - lab
Haiyuan Yu	The Yu group performs research in the broad areas of Network Systems Biology. We use integrated computational-experimental systems biology approaches to determine protein interactions and complex structures on the scale of the whole cell. In particular, we focus on protein-protein and gene regulatory networks and seek to understand how such intricate systems evolve and how their perturbations lead to human diseases, especially autism spectrum disorder and cancer.
Mariana Wolfner	Molecular and genetic mechanisms of reproductive processes, specifically functions and evolution of seminal proteins and (separately) mechanisms of egg activation and early embryogenesls - lab