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Kimaya Bakhle

Kimaya Bakhle

Concentration: Translational Medicine
Faculty Mentor:  Anushka Dongre

Brief Biography
Kimaya is originally from a suburb of Cleveland, Ohio. During high school, she worked at a small animal clinic, which sparked her interest in veterinary medicine. She pursued this interest
through a pre-veterinary biochemistry program at Purdue University. At Purdue, she also got involved in research, leading her to the Cornell Combined DVM/PhD Program. In the future, Kimaya hopes to use her background in veterinary medicine and cancer biology research to improve outcomes for animals and humans with cancer. In her free time, Kimaya enjoys working
out, trying new recipes, and exploring the outdoors with her dogs.


Education
B.S. in Biochemistry with a minor in Spanish, Purdue University, 2021
 

Research Interest Statement
Kimaya has had the opportunity to work with a variety of model organisms to investigate disease mechanisms. She first worked in a biochemistry laboratory at Purdue University, studying genetic factors involved in age-related eye disease in Drosophila melanogaster . After graduating, Kimaya joined a comparative pathology laboratory, studying changes that occur to the blood-brain barrier during tumorigenesis using a mouse model. Most recently, Kimaya studied the role of drug-metabolizing enzymes in the breed-specific predisposition of canine urothelial carcinoma. At Cornell, Kimaya hopes to pursue research on cancer biology in order to improve cancer prevention and treatment in animals and humans.
 

Publications

  • Jauregui-Lozano, J., Hall, H., Stanhope, S. C., Bakhle, K. , Marlin, M. M., & Weake, V. M. (2022). The Clock:Cycle complex is a major transcriptional regulator of Drosophila photoreceptors that protects the eye from retinal degeneration and oxidative stress. PLOS Genetics , https://doi.org/10.1371/journal.pgen.1010021
  • Jauregui-Lozano, J., Bakhle, K ., & Weake, V. M. (2021). In vivo tissue-specific chromatin profiling in Drosophila melanogaster using GFP-tagged nuclei. Genetics, Volume 218, Issue 3, https://doi.org/10.1093/genetics/iyab079
     

Presentations

  • “ Aminoisoquinolines Penetrate the Blood-Tumor Barrier and May Inhibit Metastasis of Lung Cancer to the Brain.” Minisymposium at Experimental Biology, April 2022, Philadelphia, Pennsylvania.
  • “Set1, Set2, and the Clock-cycle complex are necessary to prevent age-related retinal degeneration in Drosophila melanogaster .” Poster presentation at Experimental Biology, April 2022,  Philadelphia, Pennsylvania.
  • “A Histologic Evaluation of the Therapeutic Efficacy of Aminoisoquinolines for Brain Metastases of Lung Cancer.” Poster at American College of Veterinary Pathologists Annual Meeting, October 2021, Virtual.
  • “Genetic Factors Involved in Photoreceptor Survival.” Oral Presentation at Purdue University Office of Undergraduate Research Spring Expo, April 2021, West Lafayette, Indiana.
  • “Effects of Aging on Genes Involved in Photoreceptor Survival.” Oral Presentation at Purdue University Office of Undergraduate Research Spring Expo, April 2020, West Lafayette, Indiana.
  • “Effects of Aging on Genes Involved in Photoreceptor Survival.” Oral Presentation at Purdue University Office of Undergraduate Research Fall Expo, November 2019, West Lafayette, Indiana