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• 1994     Cornell University, Ph.D.
• 1987     Shandong Agricultural University, China, M.S.
• 1982     Shandong Normal University, China, B.S.

• 2019-current     Senior Research Associate, Cornell University Department of Clinical Sciences
• 2015-2019     Research Associate, Cornell University Department of Clinical Sciences
• 2013-2015     Postdoctoral Associate, Cornell University Department of Clinical Sciences
• 2012-2013     Research Associate, Boyce Thompson Institute, Cornell University
• 2007-2011     Postdoctoral Associate, Boyce Thompson Institute, Cornell University
• 2003-2007     Senior Biologist, Environmental Associates, Ltd, Ithaca, NY
• 1996-1999     U.S. Army Research Fellow, Cornell University Department of Cancer Pathology
• 1994-1996     Postdoctoral Research Fellow, National Institutes of Health-NIDDK, Bethesda, MD

1. Shiying Zhang, Kenneth W. Simpson (2019). Short chain fatty acids down regulate the virulence of IBD-associated E. coli  in vitro. (In preparation).
2. Shiying Zhang, Shan Gao, Zhangjun Fei, Paul Debbie, and Gary Blissard (2019). A novel method to abrogate intracellular RNA virus by co-culturing. (In preparation).
3. Mani Khoun, Belgin Dogan, Jgc, Viw, Greg Putzel, Fcd, Jeremy Herzog, Schoenbo, Ellermann, Bo Liu, White j,   Maureen Bower, Shiying Zhang, Honghe Sun,  Ajay Gulati,  Ryan Balfour Sartor, Kenneth W Simpson, Ral, and Steve Lipken (2019). Adherent-Invasive E. coli Induce Th17 Immunity and Ileocolitis in Agr2-Deficient Mice. Inflammatory Bowel Diseases. (Submitted).
4. Morteza Azizi, Meisam Zaferani, Belgin Dogan, Shiying Zhang, Kenneth W. Simpson, and Alireza Abbaspourrad (2018). Nanoliter-Sized Microchamber/Microarray Microfluidic Platform for Rapid Antibiotic Susceptibility Testing. Analytical Chemistry, DOI: 10.1021/acs.analchem.8b03817 
5. Seyed Ramin Pajoumshariati, Morteza Azizi, Shiying Zhang,  Belgin Dogan, Kenneth W Simpson, and Alireza Abbaspourrad (2018). Microbiome within a Membrane: A Microfluidic Based Model for Spatially Constrained Culture of Intestinal Microbiota. Adv. Funct. Mater. 48. DOI: 10.1002/adfm.201870339
6. Seyed Ramin Pajoumshariati, Morteza Azizi, Shiying Zhang,  Belgin Dogan, Kenneth W Simpson, and Alireza Abbaspourrad (2018). A Microfluidic-based Model for Spatially Constrained Culture of Intestinal Microbiota. Adv.  Funct. Mater. 1805568. DOI: 10.1002/adfm.201805568.
7. Shiying Zhang, Jing Fu, Belgin Dogan, Ellen J Scherl, and Simpson KW (2018). 5-Aminosalicylic acid downregulates the growth and virulence of Escherichia coli associated with IBD and colorectal cancer, and upregulates host anti-inflammatory activity.  J. Antibiot. DOI : 10.1038/s41429-018-0081-8. July 26, 2018.
8. Dogan B, Fu J, Zhang Shiying, Scherl EJ, Simpson KW (2018). Rifaximin decreases virulence of Crohn's disease-associated Escherichia coli and epithelial inflammatory responses. J Antibiot (Tokyo). 71(5):485-494.
9. Chen, Y.-R.; Zhong, S.; Fei, Z.; Gao, S.; Zhang, Shiying.; Li, Z.; Wang, P.; Blissard, G.W. (2014) Transcriptome Responses of the Host Trichoplusia ni to Infection by the Baculovirus Autographa californica Multiple Nucleopolyhedrovirus. J. Virol. 2014, 88, 13781–13797.
10. Chen, Y; Zhong, S; Fei, Z; Hashimoto, Y; Xiang, J; Zhang, Shiying; and Blissard, G (2013). The transcriptome of the baculovirus Autographa californica multiple nucleopolyhedrovirus in Trichoplusia ni cells. J. Virol.. 87, 6391-6405.
11. Shiying Zhang, Yoshi Hashimoto, Sheng Zhang, Yun-Ru Chen and Gary W Blissard (2012).Correction:  BTI-Tnao38, a new cell line derived from Trichoplusia ni, is permissive for AcMNPV infection and produces high levels of recombinant proteins. BMC Biotech, 12:12-18.
12. Shan M, Zhang Shiying, Jiang L, Ma M, Li GX (2011). Susceptibility to AcMNPV and expression of recombinant proteins by a novel cell clone derived from a Trichoplusia ni QAU-BTI-Tn9-4s cell line.  Virol Sin. 26(5):297-305. doi: 10.1007/s12250-011-3201-1.
13. Hung-Chi Cheng, Mossaad Abdel-Ghany, Shiying Zhang and Bendicht U. Pauli (1999) Is the Fisher 344/CRJ rat a protein-knock-out model for dipeptidyl peptidase IV-mediated lung metastasis of breast cancer? Clinical &Experimental Metastasis, 17:609-615.
14. Susan Pellegrino, Shiying Zhang, Anja Garritsen, and William F. Simonds (1997). The coil-coil region of the G-protein β-subunit: Mutational analysis of Gγ and effector interactions. J. Biol. Chem. 272:25360-25366.
15. Shiying Zhang, Omar A. Coso, Regina Collins, J. Silvio Gutkind and William F. Simonds (1996) Selective activation of effector pathway by brain-specific G-protein β5. J. Biol. Chem. 271:33575-33579.
16. Shiying Zhang, Omar A. Coso, Regina Collins, J. Silvio Gutkind and William F. Simonds (1996) A Carboxyl mutant of the G-protein β subunit deficient in the activation of phospholipase C-β. J. Biol. Chem. 271:20208-20212.
17. Shiying Zhang and Andre T. Jagendorf (1995) Some unique characteristics of thylakoid unisite ATPase. J. Biol. Chem. 270:6607-6614.
18. Shiying Zhang, D. D. Letham, and A. T. Jagendorf (1993). Inhibition of thylakoid ATPase by venturicidinas an indicator of CF1-CF0 interaction. Plant physiology, 101, 127-133. DOI: 10.1104/pp.101.1.127.
19. Abdel-Ghany M, el-Gendy K, Zhang, Shiying, Raden D, Racker E (1989). Brain protein kinase C phosphorylating poly(arginine,serine) or lamin B is stimulated by anions and by an activator purified from bovine serum albumin preparations. Proc. Nat. Aca. Sci. USA. 86: 1761-5. PMID 2928301.
20. S. Zhang, and G. Zhang (1986). Chapter 4: Lipids biochemistry and metabolism. Plant Biochemistry. Shandong Publisher, PP:310-398.

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