Livestock is essential to the human food supply chain and represents one of the most traded agricultural commodities globally. However, livestock diseases may negatively impact the environment by reducing output and increasing the resources needed to produce animal protein for the human population. In industrialized countries, livestock diseases significantly challenge efficiency and resource utilization. Similarly, in non-industrialized countries, cattle diseases adversely affect production levels, driving the expansion of agricultural areas. This expansion often leads to deforestation and pollution, further increasing environmental impact. Moreover, common infectious and chronic diseases in livestock increased antibiotic use, raising the risk of multi-resistant bacteria impacting human health. Extended antibiotics use, commonly applied to treat chronic diseases, may alter the animal microbiome, potentially affecting methane production in cattle. However, the direct impact of diseases in livestock on individual methane emissions remains unclear. Therefore, this proposal focuses on producing preliminary data on the effects of common infectious diseases in cattle on individual methane emissions. We will concentrate our initial efforts on confined dairy cattle systems in the US. Additional objectives of this study are i) to validate proprietary GHG low-cost sensors using the gold standard respiration chambers facilities at Cornell, ii) to develop a methodology to measure emissions from small and medium size dairy farms using proprietary GHG low-cost sensors, and iii) to study farmers' willingness to adopt these low-cost sensor nodes. This study will lead to partnerships with organizations to expand methane emissions measurements in non-industrialized countries and investigate how disease prevention can reduce the environmental impact of cattle production. We will implement the technologies and methodologies validated during the current project in non-industrialized countries where agriculture plays a significantly more prominent role in society and the economy, aiming to drive sustainable development globally.