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Susanna Babasyan, PhD

Department of Population Medicine and Diagnostic Sciences

Research Associate

Department of Population Medicine and Diagnostic Sciences
Cornell University College of Veterinary Medicine
Ithaca, NY 14853

Office: 607.253.3130
Email: sb687@cornell.edu

Education

  • 1997, Ph.D. Molecular Biology, Engelhardt Institute of Russian Academy of Sciences
  • 1988, B.S. Biochemistry, Yerevan State University

Biography/Professional Experience

  • 2014 – present, Postdoctoral Associate, College of Veterinary Medicine, Cornell University
  • 2008 - 2014, Technician, College of Veterinary Medicine, Cornell University
  • 2005 - 2008, Medical Technologist, Laboratory Alliance of CNY
  • 1998 - 2005, Scientist, Engelhardt Instititute of Molecular Biology, Moscow, Russia

Publications

  1. Schnabel CL, Babasyan S, Rollins A, Freer H, Wimer CL, Perkins GA, Raza F, Osterrieder N, Wagner B. An equine herpesvirus type 1 (EHV-1) Ab4 open reading frame (ORF)2 deletion mutant provides immunity and protection from EHV-1 infection and diseasez J Virol. 2019 Aug 28. pii: JVI.01011-19. doi: 10.1128/JVI.01011-19. [Epub ahead of print] PMID: 31462575

  2. Perkins G, Babasyan S, Stout AE, Freer H, Rollins A, Wimer CL, Wagner B. Intranasal IgG4/7 antibody responses protect horses against equid herpesvirus-1 (EHV-1) infection including nasal virus shedding and cell-associated viremia. Virology. 2019 May;531:219-232. doi: 10.1016/j.virol.2019.03.014. Epub 2019 Mar 22. PubMed PMID: 30928700.

  3. Schnabel CL, Babasyan S, Freer H, Wagner B. CXCL10 production in equine monocytes is stimulated by interferon-gamma. Vet Immunol Immunopathol. 2019 Jan;207:25-30. doi: 10.1016/j.vetimm.2018.11.016. Epub 2018 Nov 24. PubMed PMID: 30593347.

  4. Schnabel CL, Wemette M, Babasyan S, Freer H, Baldwin C, Wagner B. C-C motif chemokine ligand (CCL) production in equine peripheral blood mononuclear cells identified by newly generated monoclonal antibodies. Vet Immunol Immunopathol. 2018 Oct;204:28-39. doi: 10.1016/j.vetimm.2018.09.003. Epub 2018 Sep 11. PubMed PMID: 30596378.

  5. Wimer CL, Schnabel CL, Perkins G, Babasyan S, Freer H, Stout AE, Rollins A, Osterrieder N, Goodman LB, Glaser A, Wagner B. The deletion of the ORF1 and ORF71 genes reduces virulence of the neuropathogenic EHV-1 strain Ab4 without compromising host immunity in horses. PLoS One. 2018 Nov 15;13(11):e0206679. doi: 10.1371/journal.pone.0206679. eCollection 2018. PubMed PMID: 30440016; PubMed Central PMCID: PMC6237298.

  6. Schnabel CL, Wimer CL, Perkins G, Babasyan S, Freer H, Watts C, Rollins A, Osterrieder N, Wagner Deletion of the ORF2 gene of the neuropathogenic equine herpesvirus type 1 strain Ab4 reduces virulence while maintaining strong immunogenicity. BMC Vet Res. 2018 Aug 22;14(1):245. doi:10.1186/s12917-018-1563-4. PubMed PMID: 30134896; PubMed Central PMCID: PMC6106926.

  7. Schnabel CL, Babasyan S, Freer H, Wagner B. Quantification of equine immunoglobulin A in serum and secretions by a fluorescent bead-based assay. Vet Immunol Immunopathol. 2017 Jun;188:12-20. doi: 10.1016/j.vetimm.2017.04.001. Epub 2017 Apr 10. PubMed PMID: 28615123.

  8. Wagner B, Perkins G, Babasyan S, Freer H, Keggan A, Goodman LB, Glaser A, Torsteinsdóttir S, Svansson V, Björnsdóttir S. Neonatal Immunization with a Single IL-4/Antigen Dose Induces Increased Antibody Responses after Challenge Infection with Equine Herpesvirus Type 1 (EHV-1) at Weanling Age. PLoS One. 2017 Jan 3;12(1):e0169072. doi: 10.1371/journal.pone.0169072. eCollection 2017. PubMed PMID: 28045974; PubMed Central PMCID: PMC5207648.

  9. Wagner B, Goodman LB, Babasyan S, Freer H, Torsteinsdóttir S, Svansson V, Björnsdóttir S, Perkins GA. Antibody and cellular immune responses of naïve mares to repeated vaccination with an inactivated equine herpesvirus vaccine. Vaccine. 2015 Oct 13;33(42):5588-5597. doi:
    10.1016/j.vaccine.2015.09.009. Epub 2015 Sep 16. PMID: 26384446

  10. Perkins GA, Goodman LB, Wimer C, Freer H, Babasyan S, Wagner B. Maternal T-lymphocytes in equine colostrum express a primarily inflammatory phenotype. Vet Immunol Immunopathol. 2014 Oct 15;161(3-4):141-50. doi: 10.1016/j.vetimm.2014.07.009. Epub 2014 Aug 2. PubMed PMID: 25174977.

  11. Schnabel CL, Wagner S, Wagner B, Durán MC, Babasyan S, Nolte I, Pfarrer C, Feige K, Murua Escobar H, Cavalleri JM  Evaluation of the reactivity of commercially available monoclonal antibodies with equine cytokines. Vet Immunol Immunopathol. 2013 Nov 15;156(1-2):1-19. doi: 10.1016/j.vetimm.2013.09.012. Epub 2013 Sep 25. PMID: 24139393

  12. Wagner B, Hillegas JM, Babasyan S. Monoclonal antibodies to equine CD23identify the low-affinity receptor for IgE on subpopulations of IgM+ and IgG1+ B-cells in horses. Vet Immunol Immunopathol. 2012 Apr 15;146(2):125-34. doi: 10.1016/j.vetimm.2012.02.007. Epub 2012 Feb 18. PubMed PMID: 22405681.

  13. Rubtsov, P.M., Babasyan S., Astapova I.I., Pituitary control of differential expression of GHR in rat liver. Abs. Of 10th International Congress of Endocrinology, San-Francisco, v 2 p.806, 1996

  14. Babasyan S., Astapova I.I., Sverdlova P. S., Induction of synthesis of female – specific GHR mRNA variants in male rat liver. Molecular Biology, v. 32, 5, p. 225-228, 1997

  15. Babasyan S., Astapova I.I., Sverdlova P. S., Tissue, age and sex- specific expression of rat GHR and its regulation by GH. Abs of 2nd Congress of Biochemical Society of Russian Academy of Sciences, Moscow part 1 p. 254-255, 1997

  16. Rubtsov, P.M., Babasyan S., Sverdlova P.S., Two alternative 5’-nontranslating sequences of rat GHR mRNA have tissue-specific differences in expression. Eur. Journal of Endocrinology, v. 130, suppl 2, p. 253-258, 1994

  17. Rubtsov, P.M., Babasyan S., Zaitsev A.A., Organization and expression of genes of somatotropin/prolactin family hormone receptors. Abs. Of Congress dedicated to 80th anniversary of acad. Yudaev N. A., Moscow, v. 93 p. 21-22 1993

  18. Rubtsov, P.M., Babasyan S., Sverdlova P.S., Sex-dependent expression of alternative variants of GHR mRNA in rat liver. Molecular Biology, v. 27, 5, p.1157-1164, 1993