The focus of the lab is to understand how the immune system works and to elucidate the cellular and molecular basis of immune defects/dysfunctions that manifest in autoimmune diseases {such as MS and inflammatory bowel diseases (IBD)} or failure of the immune system to eradicate cancer. Armed with knowledge gained from these studies, we then aim to develop immune-based therapeutic approaches to mitigate or eliminate these manifestations. We therefore focus on immune regulation at systemic and mucosal sites (including the skin and the gut) and the central nervous system. To accomplish our goals, several areas of study are ongoing in the lab.

BS (Long Island University)
PhD (Albert Einstein College of Medicine) - 1999
Postdoctoral Associate/Associate Research Scientist (Yale)

Dr. Margaret Bynoe, an Associate Professor in the Department of Immunology and Infectious Diseases, received her Bachelor of Science degree in Biology from Long Island University in 1991. She received her PhD from Albert Einstein College of Medicine in 1999 where she studied the molecular basis of steroid hormones in the development of the autoimmune disease, systemic lupus erythematosus. She received her postdoctoral training in the laboratory of the late Charles A Janeway, Jr. where she studied the immunological bases of Type1 Diabetes and multiple sclerosis (MS) and later became an Associate Research Scientist at Yale University School of Medicine. Her major source of funding is the NIH and also recently the National Multiple Sclerosis Society.

• Faculty of 1000 Recognition, Immunity.  (Vol. 19:317, 2003)
• President’s Council of Cornell Women Award (2007)
• Pfizer Animal Health Award for Research Excellence (2009)
• Finalist, NIH Director’s Pioneer Award
• Faculty of 1000, Journal of Neuroscience (2012) (31(37):13272-80)
• State-of-the-art Speaker, American College of Veterinary Internal Medicine (2012)
• Lustgarten-eBioscience Memorial Award (2016)
• Recipient of the Schwartz Alumni Research Fund Award (2017)

Dr. Bynoe is a member of the following Graduate Fields:

• Comparative Biomedical Sciences
• Immunology and Infectious Disease