My laboratory is focused primarily on studying the mechanisms underlying neurologic disease in animals utilizing both spontaneously arising disease and experimental models in a variety of laboratory animal species. One current focus of my lab is in utilizing the dog as a model for human brain cancer, primarily meningeal and glial tumors. This is being done through a variety of histologic, immunohistochemical, and molecular studies in both the dog and cat. We are especially interested in determining the roles that novel gene mutations have in the genesis of canine and feline meningioma and are utilizing RNAseq to better understand the transcriptome of this tumor. We are also actively involved in studying the immune cell microenvironment in canine brain tumors in order to determine if a relationship exists between immune cell infiltration and postsurgical outcome. Other active areas of research in my laboratory include analyzing the RNA transcriptome of canine soft tissue sarcomas, a common, but understudied tumor, in the dog. Due to my expertise in nonhuman primate pathology, I maintain numerous collaborations with researchers throughout the country aiding in various research studies.

• Residency, Veterinary Anatomic Pathology, Cornell University, 2008
• DVM, Cornell University, 2005
• BS in Animal Science, Cum Laude with Distinction in Research, Cornell University, 2001

I am an Associate Professor in the College of Veterinary Medicine and Section Chief for Anatomic Pathology. I am a diplomate of the American College of Veterinary Pathologists (ACVP). I received my doctorate in veterinary medicine from Cornell University in 2005 and entered a residency in veterinary anatomic pathology at Cornell University, completed in 2008. I joined the faculty at the New England Primate Research Center, a division of Harvard Medical School as a research associate in 2008. I had achieved assistant professor by 2013 and held an appointment in the Pathology Department of the Massachusetts General Hospital during my tenure at the primate center. I joined the faculty in the Section of Anatomic Pathology as an Assistant Professor at Cornell University in fall of 2013. I have a strong interest in training veterinary students and pathology residents and preparing them for a career in comparative veterinary pathology. I believe that this is best done through hands on exposure to clinical cases and basic research techniques. I am involved nationally in the ACVP and other pathology groups including the Canine Brain Tumor Consortium, a multidisciplinary group organized through the National Cancer Institute. I strongly believe in the integration of teaching and collaborative research as a way to foster continued growth in the field of comparative veterinary pathology. 

1. Reyes VAA, Miler AD, de Lahunta A, Summers BA, Rissi DR. Canine cystic astrocytomas: 7 cases. J Vet Diagn Invest. 2025, epub Jan 27
2. Abdu A, Henry ME, André NM, Miller AD, Lejeune M, Berliner EA, Whittaker GR. Toxoplasmal meningoencephalitis in a 14 week-old shelter cat with presumed feline infectious peritonitis. Vet Parasitol Reg Stud Reports. 2025 Jan;57:101173.
3. Schultz MA, Rose JB, Olstad K, Cross JR, Holder KA, Hope KL, Richards B, Miller AD. Infarctive encephalopathy in zoo-housed gibbons in North America. Vet Pathol. 2024, epub Dec 12.
4. Korff CP, Nelissen S, Todd-Donato AB, Miller AD, Davies E. Malignant transformation of an intraparenchymal hemangioma in the cervical spinal cord of a German shepherd dog. J Vet Intern Med. 2024, 38(5):2681-2685.
5. Barrantes Murillo DF, Negrao Watanabe TT, Wiener DJ, Miller A, Rissi DR, Sandey M. Cytokeratin AE1/AE3 immunolabeling in epitheloid hemangiosarcoma. Vet Pathol. 2024; epub Aug 20 (pathology and data interpretation)
6. Rissi DR, Miller AD, Daverio H, Demeter EA, Church ME, Donovan TA. Rostral cranial fossa and sinonasal neoplasms with cribriform plate involvement in 32 dogs and 17 cats. J Vet Diagn Invest. 2024; epub Aug 17 (pathology and data interpretation)
7. Rissi DR, Miller AD. Rosettes and pseudorosettes in veterinary neuropathology. Vet Pathol. 2024; epub Aug 14.
8. Willis AT, Dahlgren AR, Woolard KD, Ghosh S, Donnelly CG, de la Concha-Bermejillo A, Pacheco A, Watson KD, Berryhill E, Aleman M, Wensley F, Humphreys S, Whitehead AE, Goldsmith D, Chesen B, Ragsdale J, Tompkins JE, Nash R, Plunkett AH, Qualls HJ, Rodriguez K, Hochanadel D, Miller AD, Finno CJ. Clinicopathological and pedigree investigation of a novel spinocerebellar disease in juvenile Quarter Horses in North America. J Vet Intern Med. 2024; 38(3):1808-1814.
9. Rissi DR, Miller AD, Demeter EA, Church MA, Koehler JW. Diagnostic immunohistochemistry of primary and secondary central nervous system neoplasms of dogs and cats. J Vet Diagn Invest. 2024; 36(2):153-168 (co-first authors)
10. Yin JH, Sexton B, Jukier T, Yanke AB, Holland M, Miller AD, Stranahan L, Hoffmann AR, Sandey M. Intraneural perineurioma in dogs: A case series and brief literature review. Front Vet Sci. 2024; Jan 11;10:1233230. (pathology and data interpretation)
11. Lection J, Wagner B, Byron M, Miller A, Rollins A, Chenier T, Cheong SH, de Amorin MD. Inflammatory markers for differentiation of endometritis in the mare. Eq Vet J. 2024. 56(4):678-687 (pathology and data interpretation)
12. Voigt AL, Nelissen S, Percival AJ, Voss HU, Lavin ES, Miller AD, Feldman ER. Spontaneous pituitary neoplasm in two female geriatric Southern giant pouched rats (Cricetomys ansorgei). Comp Med. 2023, 73(6):486-493. (pathology and data interpretation)
13. Koehler JW, Miller AD, Rissi DR. Effects of autolysis and prolonged fixation on histomorphology and immunohistochemistry of normal canine brain tissue: an experimental study. J Vet Diagn Invest. 2024, 36(2):169-176. (pathology and data interpretation)
14. Smith CR, Miller AD. In situ hybridization to detect Escherichia coli in canine granulomatous colitis. J Vet Diagn Invest. 2024, 36(1):142-145.
15. Nelissen S, Miller AD. Assessment of SOX10 expression in 437 canine neoplasms of different embryologic origins. Vet Pathol. 2024, 61(5):704-711.
16. White KS, Walker JA, Wang J, Autissier P, Miller AD, Abuelezen NN, Burrack R, Li Q, Kim WK, Williams KC. Simian immunodeficiency virus-infected rhesus macaques with AIDS co-develop cardiovascular pathology and encephalitis. Front Immunol. 2023, 14:1240946. (pathology and data interpretation)
17. Ma Y, Peng S, Donnelly CG, Ghosh S, Miller AD, Woolard K, Finno CJ. Genetic polymorphisms in vitamin E transport genes as determinents for risk of equine neuroaxonal dystrophy. J Vet Intern Med. 2023; 38(1):417-423. (pathology and data interpretation)
18. Embersics C, Bannasch D, Batcher K, Boudrea EC, Church M, Miller AD, Platt S, Koehler J, Olby N, Rossmeisl J, Rissi D, Grahn R, Donner J, Dickinson PJ. Association of the FGF4L2 retrogene with fibrocartilagenous embolic myelopathy in dogs. J Vet Intern Med. 2023, epub Nov 2 (pathology and data interpretation)
19. Ekenstedt KJ, Minor KM, Shelton GD, Hammond JJ, Miller AD, Taylor SM, Huang Y, Mickelson JR. A SACS deletion variant in Great Pyrenees dogs causes autosomal recessive neuronal degeneration. Hum Genet. 2023, 142(11):1587-1601. (pathology and data interpretation)
20. Warfield R, Robinson JA, Podgorski RM, Miller AD, Burdo TH. Neuroinflammation in the dorsal root ganglia and dorsal horn contributes to persistence of nociceptor sensitization in SIV-infected antiretroviral-therapy treated macaques. Am J Pathol. 2023, epub Sep 19 (pathology and data interpretation)
21. Fielding A, Minuto J, Mazan M, Miller AD, Newman SJ. Intracranial embryonal neoplasm in an alpaca. J Vet Diagn Invest. 2023, 35(6):777-781. (pathology and data interpretation)
22. Rissi DR, Reyes VAA, Donovan TA, Church ME, Howerth EW, Klang A, Woolard KD, Miller AD. Primary and secondary leptomeningeal gliomatosis in dogs. Vet Pathol. 2024, 61(2):171-178.
23. Rodney AR, Skidmore ZL, Grenier JK, Griffith OL, Miller AD, Chu S, Ahmed F, Bryan JN, Peralta S, Warren WC. Genomic landscape and gene expression profiles in feline oral squamous cell carcinoma. Front Vet Sci. 2023, 10:1079019. (pathology and data interpretation)
24. Peralta S, Grenier JK, Webb SM, Miller AD, Miranda IC, Parker JSL. Transcriptomic signatures of feline gingivostomatitis are influenced by upregulated IL6. Res Sq. 2023, May 3:rs.3.rs-2852140. (pathology and data interpretation)
25. Korff CP, Chu SA, Percival AJ, Nelissen S, Wood JH, Davies E, Miller AD, Newman AW. Unique cytologic and imaging features of a lumbosacral oligodendroglioma in a cat. J Vet Diagn Invest. 2023, 35(3):289-294. (pathology and data interpretation)
26. Reyes VAA, Donovan TA, Miller AD, Porter BF, Frank CB, Rissi DR. Doublecortin immunolabeling in canine gliomas with distinct degrees of tumor infiltration. J Vet Diagn Invest. 2022, 35(2):187-192. (pathology and data interpretation)
27. Nelissen S, Miller AD. Comparison of anti-Mullerian hormone and inhibin immunolabeling in canine and equine granulosa cell tumors. J Vet Diagn Invest. 2022 34(6):1027-1031.
28. Riker J, Clarke LL, Demeter EA, Miller AD, Howerth EW, Miller DM, Rissi DR. Histiocytic sarcoma with central nervous system involvement in 6 cats. J Vet Diagn Invest. 2023 35(1):87-91. (pathology and data interpretation)
29. Buote NJ, Loftus JP, Miller AD. Laparoscopic twist technique has the best overall artifact profile when comparing three laparoscopic hepatic cup biopsy techniques for dogs. Am J Vet Res. 2022, 83(12):ajvr.22.08.0127.
30. Latifkar A, Wang F, Mullman JJ, Panizza E, Fernandez IR, Ling L, Miller AD, Fischbach C, Weiss RS, Lin H, Cerione RA, Antonyak MA. IGF2BP2 promotes cancer progression by degrading the RNA transcript encoding a v-ATPase subunit. Proc Natl Acad Sci USA. 2022, 119(45):e2200477119. (pathology and data interpretation)
31. Martins M, do Nascimento GM, Nooruzzaman M, Yuan F, Chen C, Caserta LC, Miller AD, Whittaker GR, Fang Y, Diel DG. The omicon variant BA.1.1 presents a lower pathogenicity than B.1 D614G and delta variants in a feline model of SARS-CoV-2 infection. J Virol. 2022, 96(17): e0096122.
32. Holdsworth JP, Marino DJ, Loughin, Miller AD, Sackman JJ, Lesser ML, O’Donnell M. Biopsy and histologic findings of the dura mater at the level of the foramen magnum in 121 CKCS with Chiari-like malformation. Front Vet Sci 2022, 9:954092. (pathology and data interpretation; manuscript editing)
33. Cruz Otero JD, Jager M, Armien AG, Miller A, Stokol T. Granular variant of a histiocytic tumor on the toe of a cat: Case report and literature review. Vet Clin Pathol 2022, epub Jun 24. (pathology and data interpretation; manuscript editing)
34. Herberger A, Hammond J, Miller A, Olsen B. MRI of a middle ear cholesteatoma in a cat. Vet Radiol Ultrasound. 2022, 63(5):E16-E20. (pathology and data interpretation; manuscript editing)
35. Tanaka Y, Watanabe K, Miller AD, Matsumoto K, Kobayashi Y. Cholesterol granuloma associated with degenerative neuropathy in the cauda equina of a dog. J Vet Diagn Invest. 2022, 34(6):1010-1014. (pathology and data interpretation; manuscript editing)
36. Faust AE, Soletti L, Cwalina NA, Miller AD, Wood MD, Mahan MA, Cheetham J, Brown BN. Development of an acellular nerve cap xenograft for neuroma prevention. J Biomed Mater Res A. 2022 110(11):1738-1748. (pathology and data interpretation; manuscript editing)
37. Krane GA, Shockley KR, Malarkey DE, Miller AD, Miller CR, Tokarz DA, Jensen HL, Janardhan KS, Breen M, Mariani CL. Inter-pathologist agreement on diagnosis, classification, and grading of canine glioma. Vet Comp Oncol. 2022, 20(4):881-889. (pathology and data interpretation; manuscript editing)
38. Demeter E, Kent M, Glass E, Rissi D, Edwards J, Miller AD. OLIG2 immunolabeling in feline ependymoma. J Vet Diagn Invest. 2022, 34(5):898-901.
39. Lin M, Kent M, Glass EN, Jones AM, Miller AD, Demeter EA. Pathology in practice. J Am Vet Med Assoc. 2022, May 15;259(S2):1-5. (pathology and data interpretation; manuscript editing)
40. Johnson PJ, Rivard BC, Wood JH, DiRubio ML, Henry JG, Miller AD. Relationship between histological tumor margins and magnetic resonance imaging signal intensities in brain neoplasia in dogs. J Vet Inter Med. 2022, 36(3):1039-1048. (pathology and data interpretation; manuscript editing)
41. Tanaka Y, Watanabe K, Nakagun S, Miller AD, Sasaki M, Kobayashi Y. Bilateral plaque-like white matter degeneration in cerebral septal regions of a Chapman’s zebra (Equus quagga chapmani). J Comp Path. 2022, 194:54-57. (pathology and data interpretation; manuscript editing)
42. Johnson PJ, Todd-Donato AB, Miller AD, Wang Y, Holm C, Panisello-Manterelo Cl, Colon Acevedo CS, Wood JH. Association of hydromyelia and acute compressive myelopathy caused by intervertebral disk extrusion in dogs. J Vet Intern Med. 2022, 36(3):1049-1056. (pathology and data interpretation; manuscript editing)
43. Rissi DR, McHale BJ, Miller AD. Primary nervous system lymphoma in cats. J Vet Diagn Invest. 2022, 34(4):712-717.
44. Whitty JA, Miller AV, Miller AD, Carney PC, Scrivani PV. Associations between styloid process sheath CT sizes and age, body weight, and breed in horses. Vet Radiol Ultrasound. 2022, 63(4):436-449. (pathology and data interpretation; manuscript editing)
45. Healey EA, Andre NM, Miller AD, Whitaker GR, Berliner EA. Outbreak of feline infectious peritonitis (FIP) in shelter housed cats: molecular analysis of the feline coronavirus S1/S2 cleavage site consistent with a “circulating virulent-avirulent theory” of FIP pathogenesis. JFMS Open Rep. 2022, Feb 11;8(1):20551169221074226. (pathology and data interpretation; manuscript editing)

Access Dr. Miller's complete bibliography

• ACVP Mid-Career Excellence Award, 2024
• C.L. Davis Foundation Samuel W. Thompson Lecture Award, 2018
• Brittonkill Education Foundation Alumni Achievement Award, 2012

• American Society for Investigative Pathology
• American College of Veterinary Pathologists
• American Association of Veterinary Laboratory Diagnosticians
• American Association of Neuropathologists