Pharmacology & Toxicology
Research at the College of Veterinary Medicine meets the clinical and research demands of human and animal health. Consistently ranked among the top veterinary colleges in the country, the College leads in scientific discovery. Faculty expertise focuses on the interface between scientific research and clinical practice as well as a commitment to animal and human health.
| Faculty Index | Faculty A-C | Faculty D-L | Faculty M-R | Faculty S-Z |
Faculty |
Area of Interest |
Ion channel receptor and ligand interactions; NMR and molecular dynamics; molecular
neurobiology and biophysics; neurotransmitter receptors and signal transduction |
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Immune cell activation and signaling in development, response
to infection and respiratory inflammation |
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Analytical and heavy metals Toxicology in livestock and companion animals |
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| Infectious and non-infectious diseases of fish, pathogenesis of important bacterial pathogens of cultured and wild fish, evaluation of new therapeutic compounds for use in cultured food fish |
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Understanding the molecular mechanisms by which signals are
transmitted from cell surface receptors to biological effectors; identification
of new signaling molecules that influence the growth and differentiation of
mammalian cells |
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| Examination of how the chemical reactions of biology are
organized in time and space, and how this organization is harnessed by cells to
generate distinct outcomes; Molecular basis of cell growth and differentiation;
Biochemical and
genetic studies of Rab GTPases; Role of Yip family members
in membrane traffic |
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Identification and characterization of genes that are mutated
in breast tumors; Reproductive biology; investigation of the role that novel,
highly-abundant, and egg-restricted molecules play in reprogramming process;
Epigenetic regulation of preimplantation development and embryonic fate
decisions |
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Central nervous system regulation; investigations employ the
interdisciplinary approach of functional genomics; Basic mechanisms of
function, control and signaling in the cardiovascular system in health and
disease; understanding the molecular mechanisms underlying
hypertension and
heart failure and the pregnancy-induced cardiovascular syndrome pre-eclampsia |
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Developmental immunotoxicology; capacity of drugs, environmental chemicals, and dietary factors to produce
persistent immunotoxicologic responses in juvenile and adult offspring following
early life exposure; immune susceptibility to toxicants |
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Calcium as a second messenger in non-excitable cells, protein kinase C,
exocytosis proteins, ion channels in mast cells |
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| Hormonal regulation of the differentiation and function of ovarian follicles; effects of endocrine disrupting chemicals on the bovine species
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Infectious disease and host immune response |
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Ion channels and their role in inflammatory response and pain
sensation |
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Infectious
Diseases, epidemiology, and reintroduction medicine affecting Wildlife Health and Conservation |
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Biomedical imaging; cellular excitation and relaxation;
sarcoplasmic reticular calcium release channels; molecular processes underlying
excitation-contraction coupling; sarcolemnal ion channels;
molecular processes underlying cardiac stem cell and smooth
muscle cell development and function
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Transcriptional and cellular control of tissue morphogenesis; molecular and cellular events that direct the formation of tissues and organs
during vertebrate embryogenesis; cell signaling;
cellular behaviors and cell shape during development |
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Biomedical imaging; cellular excitation and relaxation;
sarcoplasmic reticular calcium release channels; molecular processes underlying
excitation-contraction coupling; sarcolemnal ion channels;
molecular processes underlying cardiac stem cell and smooth
muscle cell development and function
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Cell biology and enzymology of protein palmitoylation
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Molecular mechanisms of endocrine disruption, environmental toxicology, toxicogenomics, seasonal breeders and circadian rhythmicity |
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Cellular physiology; receptor pharmacology; membrane biophysics |
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Ion channel receptor and ligand interactions; NMR and molecular dynamics; molecular
neurobiology and biophysics; neurotransmitter receptors and signal transduction |
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Regulation of pituitary-specific gene expression by
gonadotropin-releasing hormone; Regulation of placental trophoblast cell
function by combinatorial signaling; biomaterials & drug delivery |
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Veterinary clinical pharmacology; comparative pharmacokinetic stuides in domestic animals; therapeutic drug monitoring; therapeutic regimes |
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| Molecular mechanisms regulating cellular oxidative folding and stress pathways using a combination of molecular, genetic, and biochemical techniques |
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Signal transduction and exocytosis in the pancreatic beta-cell |
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Deciphering the basic regulatory principles in signal transduction networks on a molecular level using a combination of X-ray crystallography, biophysical and cellular approaches; bacterial signaling controlling biofilm formation and pathogenicity; endocytosis in eukaryotes |
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Modulation of receptor properties by neurotransmitters and drugs |
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Genome maintenance mechanisms, cellular responses to genotoxins; mouse cancer models, DNA damage signaling, genomic instability; lung stem cells |
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Virology; Endocytosis of influenza virus; structure-function
studies on influenza HA, entry of coronaviruses and rhabdoviruses into host
cell; feline infectious peritonitis |
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Simple Mendelian Traits |
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Cell cycle regulation; cell differentiation; myeloblastic hematological tumor cell line, HL-60; Cancer chemoprevention; biomaterials & drug delivery;
oncogenes; genetics |
