Department of Clinical Sciences
Contact Information: Email: firstname.lastname@example.org, Phone: 607-253-3102
Sponsor: Cornell Joan and Sanford I. Weill Medical College, Clinical & Translational Science Center Seed Award
Grant Number: N/A.
Title: Planning Grant Award: Improved Magnetic Resonance Imaging of Larger Fracture Repair Using an Equine Model
Annual Direct Cost: $10,000
Project Period: 06/01/2012-05/31/2013
DESCRIPTION (provided by applicant): Fractures of long bones are common in people and large animals. When surgeons repair fractures, often times stainless steel implants are used. While the implants are suitable for stabilization, they create a problem when surgeons must re-evaluate the fracture site if additional pain or injury occurs. Often these complications are due to soft tissue injuries, which are not visible on standard x-rays.
MRI is superior to X-ray and CT for imaging soft tissues; however, in the presence of metal such as with stainless steel plates, MRI is prone to an artifact known as susceptibility, which creates severe distortion of the image and may hinder diagnosis. The degree of artifact is based on size, shape, amount, and composition of the metal implants. Recently, novel MRI pulse sequences have been developed to reduce this artifact in human total joint replacement; however, these metal implants differ from those used in fracture repair. It is difficult to predict the amount of susceptibility of artifact and degree of distortion that will arise from stainless steel plates.
This project proposes to test standard and novel MRI pulse sequences to reduce susceptibility artifact in a cadaveric equine model of fracture repair. The fracture site and regional soft tissues will be evaluated for injury. Visibility of normal anatomy will be assessed. Successful protocols may be used to guide future imaging of fracture repairs.