Ithaca, NY 14853-6401
The clinical pathology residency is a three year program designed to give advanced training in veterinary clinical pathology and laboratory medicine. Residents are trained under the close guidance of four board-certified clinical pathologists. We have two primary objectives
for our training program. The first objective is to train residents to
be outstanding clinical pathologists, who are well-versed in all aspects
of clinical pathology (hematopathology, cytopathology, clinical
chemistry, laboratory management, applied clinical pathology research).
The second objective is to inspire and encourage trainees to become
academic clinical pathologists, who will contribute to the advancement
and future of veterinary clinical pathology. As a result of this
training, residents are well prepared for the board certification
examination in clinical pathology by the American College of Veterinary
Pathologists (ACVP). Throughout this process we strive to maintain a fun
and cooperative learning environment that encourages scientific
curiosity, critical thinking and spirited debate.
Application to our program:
The next vacancy for a clinical pathology residency will be in July 2016 and an advertisement for this position will be posted on this site in the fall 2015. After reviewing this information, if you have any additional questions about our program, please contact the Resident Coordinator.
• Information about the requirements for applying to our program
• Information for referees
Description of the Residency Program:
During the training program, the resident will attain skills in the different disciplines of clinical pathology through:
• Diagnostic service duties.
• Teaching within the veterinary curriculum and continuing education programs.
• Hypothesis-driven applied clinical pathology research.
• A variety of structured activities, seminars and rounds within the clinical pathology lab and within the College of Veterinary Medicine.
Additional information on these major areas of study during the residency is given below. A more detailed description of the residency program at Cornell can be found in this document: Residency Training Guidelines. We follow training guidelines endorsed by the American Society of Veterinary Clinical Pathology (ASVCP) – see links below.
The clinical pathology residency is highlighted in the February 2011 'Scopes magazine from Cornell's College of Veterinary Medicine.
Diagnostic Service Duties:
Residents participate in daily cytology/hematology read-out sessions at least two weeks a month during the first two years of the program. In consultation with the pathologist on duty, residents review and prepare diagnostic reports for clinical cases submitted to the clinical pathology laboratory. We have a rich and varied caseload from the Cornell University Hospital for Animals consisting of 73% small animals, 25% large animals and 2% exotics, in addition to a large number of cases submitted from national and international sources via the Animal Health Diagnostic Center. Training is also provided on the performance and interpretation of specialized diagnostic testing such as flow cytometry, protein electrophoresis, cytochemistry and immunocytochemistry. As the training progresses, residents are given increasing responsibility with the goal of independence (assuming full responsibility for laboratory results) during the final year of the program.
Residents are involved in a variety of teaching activities including:
• Leading small group teaching sessions for senior veterinary students.
• Assisting in the organization and teaching of a comprehensive clinical pathology course. Residents assist in the preparation and delivery of laboratory sessions during the first and second year of their residency. During the second year of the program, residents are given the opportunity to take a more active role in clinical pathology instruction through didactic lectures. In the final year of the program, residents may also moderate a large group discussion.
• Assisting in the organization and leading of clinical pathology rounds held every two weeks, during which recent cases of interest are presented to faculty, residents and students.
• Assisting in the organization and teaching of continuing education seminars offered at the College of Veterinary Medicine, e.g. New York State Veterinary Conference.
The resident will perform applied clinical pathologic-related research under the supervision of the clinical pathologists beginning in the first year of the program. Prospective, hypothesis-driven research is expected and will culminate in the publication of results in a peer-reviewed journal as well as presentation of results at the annual meeting of the ACVP. During the course of their research, residents will acquire skills in study design, laboratory techniques and scientific writing. Residents are also required to take a statistical course during their training program. Residents are also encouraged to publish individual case reports, submit mystery slide cases for presentation at the annual meeting of the ACVP, and participate in collaborative research with other members of the college community. For further information on research interests of the current faculty and research projects undertaken by current and previous residents refer to the information provided below under the clinical pathology team.
Structured activities, seminars and rounds:
The residency training program is structured, with the residents spending substantial quality time with all board-certified clinical pathologists. These structured activities are designed to give residents thorough training for success in a variety of career opportunities in clinical pathology by enhancing diagnostic skills, providing access to infrequent disorders that may not be encountered during the residency, and assisting in preparation for the board certification examination by the ACVP. These activities include:
• Weekly case seminars: Residents are given cytology, hematology or surgical biopsy cases for description and interpretation. Starting in the second year, residents are encouraged to write a “board-style” description and interpretation.
• Biweekly or monthly chemistry case reviews: Residents are given clinical chemistry data for interpretation and critical discussion. Starting in the second year, residents are encouraged to write a “board-style” interpretation.
• Biweekly or monthly cytology-histology correlate sessions: Residents and faculty participate in the review and comparison of cytology and histopathology findings of cases, some of which are controversial and challenging.
• Biweekly seminars on special topics in clinical pathology: Each member of the clinical pathology team (residents and faculty) rotates leading discussions on principles of clinical pathology. These seminars may include review of journal articles, methodologies or other topics relating to laboratory medicine.
• Residents are encouraged to participate in a variety of other seminars and rounds held within the College of Veterinary Medicine (e.g. oncology rounds, tumor board, neuropathology rounds, wildlife pathology rounds, infectious disease forums).
To facilitate training, we have a wealth of archived resources that are available for directed and self-study. These resources include:
• An extensive textbook-based and on-line library.
• An extensive image database, including Aperio-digitally scanned slides.
• PowerPoint presentations, lecture notes, and course notes from continuing education seminars held at Cornell University or obtained from other meetings
• Slide sets:
o Resident training slides (hematology, cytology and surgical biopsy) that encompass
interesting or challenging cases.
o Extensive archived hematology and chemistry slides from routine diagnostic evaluation
including samples from normal tissues.
o Mystery slide sets from ASVCP meetings.
• Examples of normal and abnormal results, including artifacts using the following techniques:
o ADVIA hematology analyzer
o Protein electrophoresis
o Flow cytometry
• Complete case material from interesting cases (representing all species)
The Clinical Pathology Team:
In addition to the faculty and residents listed below, the clinical pathology team consists of a laboratory manager, 7 medical technologists and 2 administrative assistants. We all work together as a team to provide excellent service to our clients while maintaining a stimulating and fulfilling work environment.
Tracy Stokol, DVM, PhD, Dipl. ACVP (Clinical Pathology)
Research interests: Hemostasis, oncology, laboratory management
Erica Behling-Kelly, DVM, PhD, Dipl. ACVP (Clinical Pathology)
Title: Assistant Professor
Research interests: Lipid-based modulation of cell function, thrombosis, vascular disease
Laura Brandt, DVM, MS, Dipl. ACVP (Clinical Pathology)
Research Interests: Urine protein biomarkers of diseases.
Congratulations to Dr. Brandt for passing the certifying examination of the American College of Veterinary Pathologists in Clinical Pathology.
Ashleigh Newman, VMD, Dipl. ACVP (Clinical Pathology)
Congratulations to Dr. Newman for passing the certifying examination of the American College of Veterinary Pathologists in Clinical Pathology.
Midori Asakawa, BVSc, Dipl. ACVP (Anatomic and Clinical Pathology), 3rd Year Resident
Research project(s): Effects of lipoproteins on fibrinolysis in the dog.
Congratulations to Dr. Midori Asakawa, our current 3rd Year Resident, for passing the certifying examination of the American College of Veterinary Pathologists in Clinical Pathology and for receiving the 2014 Share the Future Research Grant from the American Society for Veterinary Clinical Pathology (ASVCP). The award is for her project with Dr. Behling-Kelly on lipoprotein modulation of fibrinolysis in the dog. Additional congratulations to Dr. Asakawa for winning the best overall presentation for her abstract with Dr. Behling-Kelly on "Canine Lipoproteins Enhance Fibrinolysis And Alter Fibrin Clot Structure” at the annual Clinical Investigator Day at the College of Veterinary Medicine, Cornell University, October 2015.
Daniela Hernandez Muguiro BVSc, MS
Research project: Immunocytochemistry on destained cytology smears, Complement activation in canine immune-mediated hemolytic anemia; A novel prognostic and therapeutic approach.
Congratulations to Dr. Daniela Hernandez, our 1st Year Resident on receiving the 2015 Share the Future Research Grant from the American Society for Veterinary Clinical Pathology (ASVCP). The award is for her project with Dr. Behling-Kelly on phosphorylated histones as a marker of mitotic index in dogs with lymphoma. Additional congratulations to Dr. Hernandez for winning the best abstract award for her abstract with Dr. Stokol on the "Effect Of Various Anti-Platelet Drugs On Ex Vivo Equid Herpesvirus Type 1-Induced Platelet Activation” at the annual Clinical Investigator Day at the College of Veterinary Medicine, Cornell University, October 2015.
Past Trainees (since 1993):
Ashleigh Newman, VMD, Dipl. ACVP (Clinical Pathology) 2012-2015
Research projects(s): Lipoprotein profiles in lactating dairy cattle. Reporting and interpreting red blood cell morphology.
Grants and Awards: Best presentation style at the Clinical Investigators Day, Cornell University (2014)
Current position: Senior Resident, Cornell University
Erika Gruber, DVM, Dipl. ACVP (Clinical Pathology) 2010-2013
Research project(s): Thrombin generation in canine cancer cells.
Grants and Awards: Travel award, ASVCP (2012), Young Investigator Award, ASVCP (2012), Best overall presentation at Resident Seminar Symposium, Cornell University (2013)
Current position: PhD student, Cornell University
Nora Springer, DVM, Dipl. ACVP (Clinical Pathology) 2009-2012
Research project(s): Platelet-derived microparticles and thrombin generation in horses. Diagnostic utility of glutamate dehydrogenase in birds.
Grants and awards: Travel award, ASVCP (2010), Share the Future training grant, ASVCP (2010), Comparative Cancer Biology Training Grant (2010), Award of Excellence for Best Large Animal Presentation at Resident Seminary Symposium, Cornell University (2012)
Current position: PhD student, Cornell University
Seigo Ogasawara, BVSc 2007-2010
Research project(s): Effect of interleukin-6, interleukin-8 and interleukin-10 on tissue factor expression in canine monocytes.
Grants and awards: Travel award, ASVCP (2009)
Current position: PhD student, Kitasato University, Japan
Heather Priest, DVM, Dipl. ACVP (Clinical Pathology) 2006-2009
Research project(s): Transferrin receptor expression in canine lymphoma.
Grants and awards: Travel award, ASVCP (2008)
Young investigator award, ASVCP (2008)
Current position: Lecturer, College of Veterinary Medicine, Cornell University
Amy Warren, BVSc, PhD Dipl. ACVP (Anatomic and Clinical Pathology) 2006-2007
Research project(s): Effect of storage on bovine hematologic parameters.
Current position: Associate Professor, University of Calgary, Canada
Chris Mesher, DVM, Dipl. ACVP (Clinical Pathology) 1993-1996
Current position: Phoenix Veterinary Laboratories, Seattle, USA
Publications from our residents
1. Gruber E, Catalfamo J, Stokol T (2015) Tissue factor drives thrombin generation in canine mammary tumor cells. Am J Vet Res. Accepted for publication
2. Newman A, Mann S, Nydam DV, Overton T, Behling-Kelly E. Impact of dietary plane of energy during the dry period on lipoprotein parameters in the transition period in dairy cattle. J Anim Physiol Anim Nutr (Berl) 2015 May 9. doi: 10.1111/jpn.12343. [Epub ahead of print]. Link to Pubmed
3. Newman AW, Rishniw M, Behling-Kelly E (2014) Reporting and interpreting red blood cell morphology: is there discordance between clinical pathologists and clinicians? Vet Clin Pathol.43: 487-495. (Editor’s choice article) Link to Pubmed
4. Newman A, Estey C, McDonough SP, Cerda-Gonzalez S, Larsen M, Stokol T (2015) Cholesteatoma and meningoencephalitis in a dog with chronic otitis externa. Vet Clin Pathol. 44:157-163. doi: 10.1111/vcp.12212. Link to Pubmed
5. Asakawa MG, Lewis SM, Buckles E, Stokol T (2015) What is your diagnosis? Cutaneous mass in a dog (granular variant of a trichoblastoma). Epub ahead of print, August 19. Vet Clin Pathol. doi: 10.1111/vcp.12280. Link to Pubmed
6. Springer NL, Smith E, Brooks MB, Stokol T (2014) Flow cytometric detection of circulating platelet-derived microparticles in clinically healthy adult horses. Am J Vet Res. 75:879-885. Link to Pubmed
7. Warren A, Stokol T, Hecker K, Nydam DV (2013) Storage-associated changes in the bovine hemogram with the ADVIA 120 hematology analyzer. Comp Clin Pathol. 22:1235-1240. doi: 10.1007/s00580-012-15569.
8. Ogasawara S and Stokol T (2012) Canine recombinant interleukin-10 inhibits lipopolysaccharide-induced upregulation of tissue factor procoagulant activity in canine peripheral blood monocytes. Vet Immunol Immunopathol. 148: 331-336. Link to Pubmed
9. Ogasawara S, Daddona J, Trimpert J, Stokol T (2012) The effect of canine recombinant interleukin-6 and interleukin-8 on tissue factor procoagulant activity in canine peripheral blood mononuclear cells and monocytes. Vet Clin Pathol. 41:325-335. Link to Pubmed
10. Priest H, McDonough SM, Erb H, Daddona J, Stokol T (2011) Transferrin receptor expression in canine lymphoma. Vet Pathol. 48:466-474. Link to Pubmed
11. Mesher CI, Blue JT, Guffroy MR, De Lahunta A (1996) Intracellular myelin in cerebrospinal fluid from a dog with myelomalacia. Vet Clin Pathol. 25:124-126. Link to Pubmed
12. Mesher CI (1997) What is your diagnosis? Subcutaneous nodule from a 14-month-old cat. Vet Clin Pathol. 26:4. Link to Pubmed
13. Mesher CI, Mauldin EA (1996) What is your diagnosis? Liver impression smears from 5 juvenile canaries. Vet Clin Pathol. 24:140. Link to Pubmed
14. Mesher CI, Rej R and Stokol T (1998) Alanine aminotransferase apoenzyme in dogs. Vet Clin Pathol. 24:26-30. Link to Pubmed
Ithaca and the Cornell University Community
Cornell University, a member of the Ivy League, provides an educationally diverse environment consisting of nearly 100 academic departments. Cornell is located in Ithaca on the shores of Cayuga Lake in the beautiful Finger Lakes region of New York. Ithaca is a vibrant city with many art museums, theaters, and a diverse selection of restaurants. It is within driving distance of several large metropolitan centers, award-winning wineries, and is a nature-lover’s paradise being surrounded by the world-famous Cornell Plantations, Sapsucker Woods Sanctuary home of the Cornell Laboratory of Ornithology, and five breathtaking State Parks. Ithaca provides the outdoor enthusiast with ample opportunity for hiking, camping, horseback riding, swimming, sailing, bird watching, snowshoeing, and cross country skiing.
Information on living in Ithaca: http://www.visitithaca.com/
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International applicants may wish to consult the International Student and Scholars Office at Cornell University website:
American College of Veterinary Pathologists
American Society for Veterinary Clinical Pathology
Guidelines for resident training in veterinary clinical pathology. I. Clinical chemistry.
Guidelines for resident training in veterinary clinical pathology. II. Hematology.
Guidelines for resident training in veterinary clinical pathology. III. Cytopathology and surgical pathology.
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