Department of Population Medicine & Diagnostic Sciences


Edward J. Dubovi

Dr. Dubovi

 

 

Professor of Virology
Director-Virology Laboratory
Animal Health Diagnostic Center
College of Veterinary Medicine
Cornell University
P. O. Box 5786
Ithaca, New York 14851-5786
607-253-3923, ejd5@cornell.edu



Research Interests


Dr. Dubovi's main areas of research include viral diseases of cattle with particular emphasis on bovine viral diarrhea virus, viral diseases of dogs with emphasis on canine influenza virus, and viral diseases of domestic animals that impact endangered wildlife. Within the context of the Department of Population Medicine and Diagnostic Sciences, current efforts also included herd health programs that emphasize biosecurity and effective use of veterinary biologicals.

 

Education

  • B.A. - Biology, 1967 University of Pennsylvania - Philadelphia, PA
  • M.A. - Virology, 1968 Purdue University - West Lafayette, IN
  • Ph.D. - Microbiology, 1975 University of Pittsburgh School of Medicine - Pittsburgh, PA


Research and Professional Experience

  • 10/04-present Professor of Virology
  • 3/02-4/03 Associate Director for Laboratory Operations, Animal Health Diagnostic Laboratory, Dept of Pop Med and Diag. Science, College of Veterinary Medicine at Cornell.
  • 2/01-3/02 Associate Chair of Diagnostic Programs, Dept of Pop Med and Diag. Science, College of Veterinary Medicine at Cornell.
  • 7/98-7/99 Associate Chair of Diagnostic Programs, Dept of Pop Med and Diag Science, College of Veterinary Medicine at Cornell.
  • 7/90-7/98 Associate Director, Diagnostic Center, College of Veterinary Medicine at Cornell
  • 11/87-9/04 Associate Professor, Dept Pop Med and Diag Science, College of Veterinary Medicine at Cornell
  • 11/81-11/87 Assistant Professor, Diagnostic Laborartory, New York State College of Veterinary Medicine at Cornell.
  • 9/77 - 11/81 Research Assistant Professor of Pediatrics and Bacteriology, University of North Carolina at Chapel Hill.
  • 7/76 - 8/77 U.S.P.H.S. Research Fellowship, Department of Microbiology, School of Medicine, University of Virginia.


Honors and Awards

  • American College of Veterinary Microbiologists - Elected Honorary Diplomate, November, 2000

 

Professional Society Memberships

  • American Society for Microbiology
  • Conference of Research Workers in Animal Diseases
  • Infectious Disease Society of America
  • American Society for Virology
  • American Association of Veterinary Laboratory Diagnosticians
  • American Association for the Advancement of Science
  • United States Animal Health Association
  • Wildlife Diseases Association
  • Sigma Xi
  • Member, Foreign and Emerging Diseases, USAHA
  • Member, Infectious Diseases of Cattle, Bison and Camelids USAHA
  • Member, Virology Committee, American Association of Veterinary Laboratory Diagnosticians
  • Member, Bluetongue and Related Orbivirus, USAHA
  • Member, Bluetongue Diagnosis Committee, American Association of Veterinary Laboratory Diagnosticians.
  • Ad Hoc Reviewer for USDA Grants Program
  • Ad Hoc Reviewer for the Grayson-Jockey Club
  • Editorial Board - Journal of Clinical Microbiology, 1992-4.
  • Ad Hoc Reviewer for the following journals:

    Journal of Virology
    Journal of Infectious Diseases
    Veterinary Pathology
    Nucleic Acids
    The Compendium on Continuing Education for the Practicing Veterinarian
    Reviews of Infectious Diseases
    Virology
    Journal of General Virology
    Journal of Clinical Microbiology
    Veterinary Microbiology
    Archives of Virology
    Journal of Veterinary Diagnostic Investigation
    Journal of Zoo and Wildlife Medicine
    Journal of Wildlife Diseases
    Journal of Virological Methods
    Virus Research
    Theriogenology
    Vaccine
    Journal of American Veterinary Medical Association
    Canadian Journal of Veterinary Research

 

Selected Publications

  1. Renshaw R, Laverack M, Zylich N, Glaser A, Dubovi E. 2011. Genomic analysis of a pneumovirus isolated from dogs with acute respiratory disease. Vet Microbiol 150:88-95.
  2. Bedenice D, Dubovi E, Kelling CL, Henningson JN, Topliff CL, Parry N. 2011. Long-term clinicopathological characteristics of alpacas naturally infected with bovine viral diarrhea virus type 1b. J Vet Intern Med 25:605-12.
  3. Percopo CM, Dubovi EJ, Renshaw RR, Dyer KD, Domachowskie JB, Rosenberg HF. 2011. Canine pneumovirus replicates in mouse lung tissue and elicits inflammatory pathology. Virology 416:26-31.
  4. Woodroffe R, Prager KC, Munson L, Conrad PA, Dubovi EJ, Mazet JA. 2012. Contact with Domestic Dogs Increases Pathogen Exposure in Endangered African Wild Dogs (Lycaon pictus). PLoS One. 7 (1):e30099. Epub 2012 Jan 6.
  5. Goodman LB, Wimer C, Dubovi EJ, Gold C, Wagner B. Immunological correlates of vaccination and infection for equine herpesvirus type 1. Clin Vaccine Immunol. 2011 Dec 28. [Epub ahead of print].
  6. Allison AB, Harbison CE, Pagan I, Stucker KM, Kaelber JT, Brown JD, Ruder MG, Keel MK, Dubovi EJ, Holmes EC, Parrish CR. 2012. Role of multiple hosts in the cross-species transmission and emergence of a pandemic parvovirus. J Virol. 86 (2):865-72. Epub 2011 Nov 9.
  7. Kapoor A, Mehta N, Dubovi EJ, Simmonds P, Govindasamy L, Medina JL, Street C, Shields S, Lipkin WI. 2011. Characterization of Novel Canine Bocaviruses and their Association with Respiratory Disease. J Gen Virol. 93:341-6
  8. Digangi BA, Gray LK, Levy JK, Dubovi EJ, Tucker SJ. 2011. Detection of protective antibody titers against feline panleukopenia virus, feline herpesvirus-1, and feline calicivirus in shelter cats using a point-of-care ELISA. J Feline Med Surg. 13 (12):912-8. Epub 2011 Aug 31.
  9. Kapoor A, Simmonds P, Dubovi EJ, Qaisar N, Henriquez JA, Medina J, Shields S, LipkinWI. 2011. Characterization of a canine homolog of human Aichivirus. J Virol. Nov;85 (21):11520-5. Epub 2011 Aug 31.
  10. Burbelo PD, Dubovi EJ, Simmonds P, Medina HL, Henriquez JA, Mishra N, WagnerJ, Tokaz R, Cullen JM, Landarola MJ, Rice CM, Lipkin WI, Kapoor A. 2012. Serology-enabled discovery of genetically diverse hepaciviruses in a new host. J Virol. 86:6171-8
  11. Lister AL, Pressler B, Volpe A, Dubovi E. 2012. Accuracy of point-of-care ELISA test kit for predicting he presence of protective canine parvovirus and canine distemper virus antibody concentrations in dogs. Vet J. Feb 28.
  12. Pinto P, Wang Q, Chen N, Dubovi EJ, Daniels JB, Millward LM, Buonavoglia C, Martella V, Saif LJ. 2012. Discovery and genomic characterization of noroviruses from a gastroenteritis outbreak in domestic cats in the US. PLoS One. 7(2):e32739.
  13. Gray LK, Crawford PC, Levy, Dubovi EJ. 2012. Comparison of two assays for detection of antibodies against canine parvovirus and canine distemper virus in dogs admitted to a Florida animal shelter. J am Vet Med Assoc. May 1;240(9):1084-7
  14. Anderson TC, Crawford PC, katz JM, Dubovi EJ, Landolt G, Gibbs EP. 2012. Diagnostic performance of the canine influenza A virus subtype H3N8 hemagglutination inhibition assay. J Vet Diagn Invest 24(3):499-508.
  15. Regan AD, Millet JK, Tse LP, Chilag Z, Rinaldi VD, Licitra BN, Dubovi EJ, Town CD, Whittaker GR. 2012. Characterization of a recombinant canine coronavirus with a distinct receptor-binding (S1) domain. Virology 430(2):90-9.
  16. Kapoor A, Dubovi EJ, Henriquez-Rivera JA, Lipkin WI. 2012. Complete genome sequence of the first canine circovirus. J Virol 86(12):7018.
  17. Kirchgessner MS, Dubovi EJ, Porter WF, Zylich, NC, Whipps CM. 2012. Prevalence and spatial distribution of antibodies to bovine viral diarrhea virus and Coxiella burnetii in white-tailed deer (Odocoileus virginianus) in New York and Pennsylvania. J Zoo Wildl Med: 43(3);466-72.
  18. Renshaw RW, Wise A, Maes R, Dubovi EJ. 2012. Complete genome sequence of a polyomavirus isolated from horses. J Virol 86(16):8903.
  19. DiGangi BA, Levy JK, Griffin B, McGorray SP, Dubovi EJ, Dingman PA, Tucker SJ. 2012. Prevalence of serum antibody titers against feline panleukopenia virus, feline herpesvirus 1, and feline calicivirus in cats entering a Florida animal shelter. J Am Vet Med Assoc. 2012 Nov 15;241(10):1320-5. doi: 10.2460/javma.241.10.1320
  20. Anderson TC, Crawford PC, Dubovi EJ, Gibbs EP, Hernandez JA 2013. Prevalence of and exposure factors for seropositivity to H3N8 canine influenza virus in dogs with influenza-like illness in the United States. J Am Vet Med Assoc. 2013 Jan 15; 242(2):209-16. doi: 10.2460/javma.242.2.209. PubMed PMID: 23276098.
  21. Nikolin VM, Osterrieder K, von Messling V, Hofer H, Anderson D, Dubovi E, Brunner E, East ML. 2012. Antagonistic pleiotropy and fitness trade-offs reveal specialist and generalist traits in strains of canine distemper virus. PLoS One.
    2012;7(12):e50955. doi: 10.1371/journal.pone.0050955. Epub 2012 Dec 11. PubMed PMID: 23239996; PubMed Central PMCID: PMC3519774.
  22. Allison AB, Kohler DJ, Fox KA, Brown JD, Gerhold RW, Shearn-Bochsler VI, Dubovi EJ, Parrish CR, Holmes EC. 2012. Frequent Cross-Species Transmission of Parvoviruses Among Diverse Carnivore Hosts. J Virol. 2012 Dec 5. [Epub ahead of print] PubMed PMID: 23221559.
  23. Kirchgessner MS, Dubovi EJ, Porter WF, Zylich NC, Whipps CM. 2012. Disease risk surface for Coxiella burnetii seroprevalence in white-tailed deer. 2012. Zoonoses Public Health. Nov 26. Doi: 10.1111/zph. 12023.
  24. Keller SM, Gabriel M, Terio KA, Dubovi EJ, VanWormer E, Sweitzer R, Barret R, Thompson C, Purcell K, Munson L. 2012. Canine distemper in an isolated population of fishers (Martes pennanti) from California. J Wildl Dis. 2012 Oct;48(4):1035-41. doi:10.7589/2011-12-350. PubMed PMID: 23060505.
  25. Ledbetter EC, da Silva EC, Kim SG, Dubovi EJ, Schwark WS. 2012. Frequency of spontaneous canine herpesvirus-1 reactivation and ocular viral shedding in latently infected dogs and canine herpesvirus-1 reactivation and ocular viral shedding induced by topical administration of cyclosporine and systemic administration of corticosteroids. Am J Vet Res. 2012 Jul;73(7):1079-84. doi: 10.2460/ajvr.73.7.1079. PubMed PMID: 22738061.
  26. Anderson DE, Dubovi EJ, Yu M, Wang LF, Renshaw RW. 2012. Genome characterization of Salem virus reveals its evolutionary intermediate status in the subfamily Paramyxovirinae. Arch Virol. 2012 Oct;157(10):1989-93. Epub 2012 Jun 23. PubMed PMID: 22729563.
  27. Kirchgessner MS, Dubovi EJ, Whipps CM. 2012. Seroepidemilogy of Coxiella burnetii in wild white-tailed deer (Ondocolileus virginianus) in New York. Vector Borne Zoonotic Dis. Nov;12(11):942-7. doi:10.1089/vbz.2011.0952.

Wildlife Related Publications

  1. House, J. A., Gregg, D. A., Lubroth, J., Dubovi, E. J., and Torres, A., 1991. Experimental equine herpesvirus-1 infection in llamas (Lama glama). J. Vet. Diagn. Invest. 3:137-143.
  2. Kimber, K.R., Kollias, G.V., and Dubovi, E.J., 2000. Serologic survey of selected viral agents in recently captured wild North American river otters (Lontra canadensis). J Zoo Wild Medicine 31(2): 168-175.
  3. Kimber , K.R., DeMaar, T., Lubroth, J., Dubovi, E.J., and Berninger, M.L. 2002. Serologic survey of selected viral, bacterial and protozoal agents in captive and free ungulates from central Kenya. Proc. NY Acad Sciences 969:217-223.
  4. Harrison, T.M., Mazet, J.K., Holekamp, K.E., Dubovi, E., Engh, A.L., Nelson, K., Van Horn, R.C., and Munson, L. 2004.Antibodies to canine and feline viruses in spotted hyenas (Crocuta crocuta) in the Masai Mara national reserve. J. Wildlife Dis. 40: 1-10.
  5. Fiorello, C.V., Deem, S.L., Gompper, M.E., and Dubovi, E.J. 2004. Seroprevalence of pathogens in domestic carnivores on the border of Madidi National Park, Bolivia. Animal Conservation 7:45-54.
  6. Munson, L., Marker L., Dubovi, E., Spencer, J.A., Everman, J.F., and O’Brien, S.J. 2004. Serosurvey of viral infections in free-ranging Namibian cheetahs (Acinonyx jubatus). J. Wildlife Dis. 40:23-31.
  7. McFadden, K.W., Wade, S.E., Dubovi, E.J., and Gompper, M.E. 2005. A serology and fecal parsitology survey of the critically endangered pygmy raccoon (Procyon pygmaeus). J Wildlife Diseases, 41:615-617.
  8. Luebcke E, Dubovi E, Black D, Ohsawa K, and Eberle R. 2006. Isolation and characterization of a chimpanzee alphaherpesvirus. J Gen Virol. 87:11-19.
  9. Clifford DL, Mazet JAK, Dubovi EJ, Garcelon DK, Coonan TJ, Conrad PA, and Munson L. 2006. Pathogen exposure in endangered island fox (Urocyon littoralis) populations: Implications for conservation management. Biol Conservation 131:230-243.
  10. Qin Q, Wei, F, Dubovi, EJ, and Loeffler IK. 2007. Serosurvey of infectious disease agents of carnivores in captive red pandas (Ailurus fulgens) in China. J. Zoo Wildl. Med. 38:42-50.
  11. Fiorello CV, Noss AJ, Deem SL, Maffei L, and Dubovi EJ. 2007. Serosurvey of small carnivores in the Bolivian Chaco. J Wildl Dis 43: 551-557.
  12. Loeffler IK, Howard J, Montali RJ, Hayek L-A, Dubovi E, Zhang Z, Yan Q, Guo W, and Wildt DE. 2007. Serosurvey of ex situ giant pandas (Ailuropoda melanoleuca) and red pandas (Ailurus fulgens) in China with implications for species conservation. J. Zoo Wildl. Med 38: 559-566.
  13. Levy JK, Crawford PC, Lappin MR, Dubovi EJ, Levy MG, Alleman R, Tucker SJ, and Clifford SL. 2008. Infectious diseases ofdogs and cats on Isabela Island, Galapogos. J Vet Intern Med. 22: 60-65.
  14. Bronson E, Emmons LH, Murray S, Dubovi EJ, and Deem SL. 2008. Serosurvey of pathogens in domestic dogs on the border of Noel Kempff Mercado National Park, Bolivia. J Zoo Wildl Med. 39: 28-36.
  15. Munson L, Terio KA, Kock R, Mlengeya T, Roelke ME, Dubovi EJ, Summers B, Sinclair AR, and Packer C. 2008. Climate extremes promote fatal co-infections during canine distemper epidemics in African lions. PloS ONE 3:e2545.
  16. Woodroffe R, Prager KC, Munson L, Conrad PA, Dubovi EJ, Mazet JA. 2012. Contact with Domestic Dogs Increases Pathogen Exposure in Endangered African Wild Dogs (Lycaon pictus). PLoS One. 7 (1):e30099. Epub 2012 Jan 6.
  17. Allison AB, Harbison CE, Pagan I, Stucker KM, Kaelber JT, Brown JD, Ruder MG, Keel MK, Dubovi EJ, Holmes EC, Parrish CR. 2012. Role of multiple hosts in the cross-species transmission and emergence of a pandemic parvovirus. J Virol. 86 (2):865-72. Epub 2011 Nov 9.
  18. Kirchgessner MS, Dubovi EJ, Porter WF, Zylich, NC, Whipps CM. 2012. Prevalence and spatial distribution of antibodies to bovine viral diarrhea virus and Coxiella burnetii in white-tailed deer (Odocoileus virginianus) in New York and Pennsylvania. J Zoo Wildl Med: 43(3);466-72.
  19. Allison AB, Kohler DJ, Fox KA, Brown JD, Gerhold RW, Shearn-Bochsler VI, Dubovi EJ, Parrish CR, Holmes EC. 2012. Frequent Cross-Species Transmission of Parvoviruses Among Diverse Carnivore Hosts. J Virol. 2012 Dec 5. [Epub ahead of print] PubMed PMID: 23221559.
  20. Kirchgessner MS, Dubovi EJ, Porter WF, Zylich NC, Whipps CM. 2012. Disease risk surface for Coxiella burnetii seroprevalence in white-tailed deer. 2012. Zoonoses Public Health. Nov 26. Doi: 10.1111/zph. 12023.
  21. Keller SM, Gabriel M, Terio KA, Dubovi EJ, VanWormer E, Sweitzer R, Barret R, Thompson C, Purcell K, Munson L. 2012. Canine distemper in an isolated population of fishers (Martes pennanti) from California. J Wildl Dis. 2012 Oct;48(4):1035-41. doi:10.7589/2011-12-350. PubMed PMID: 23060505.
  22. Kirchgessner MS, Dubovi EJ, Whipps CM. 2012. Seroepidemilogy of Coxiella burnetii in wild white-tailed deer (Ondocolileus virginianus) in New York. Vector Borne Zoonotic Dis. Nov;12(11):942-7. doi:10.1089/vbz.2011.0952.