Department of Molecular Medicine  

Department of Molecular Medicine Events

Research Work-in-Progress

Moleculare Medicine Areas of Research Moleculare Medicine Areas of Research Moleculare Medicine Areas of Research Moleculare Medicine Areas of Research Moleculare Medicine Areas of Research Moleculare Medicine Areas of Research Moleculare Medicine Areas of Research

Fall 2016 / Winter 2017

4:00 pm Mondays, November - December, Boyce Thompson Auditorium



November 7
Chris Hosford (Chappie Lab) - Assessing species-specific determinants of McrB-DNA binding
Aravind Sivakumar (Kurpios Lab) - Hyaluronan provides a mechanism for asymmetric gut and vascular morphogenesis

November 14
Bill Katt (Cerione Lab) - Examining the roles of liver-type and kidney-type glutaminase in breast cancer
Frances Chen (Kurpios Lab) - CRISPR/Cas9 genome editing at the Pitx2 locus: Investigating a role for the long noncoding RNA Playrr in transcriptional regulation of organogenesis

November 21
Stella Li (Cerione Lab) - Mechanistic basis of glutaminase activation: A key enzyme that promotes glutamine metabolism in cancer cells
Akira Karasawa (Kawate Lab) - Molecular mechanism underlying ATP-gated ion channel antagonism

November 28
Shawn Milano (Cerione Lab) - Identification of a novel region in heterotrimeric G proteins important for effector binding and activation
Joe Druso (Cerione Lab) - Effects of constitutively-active Cdc42 on primary mammary epithelia


December 5 - NO WIP, Special Seminar

December 12
Ian Malgapo (Linder Lab) - Optimization of crystallization conditions of DHHC
John O'Donnell (Sondermann Lab) - Comparing the mechanisms of GTP-hydrolysis driven conformational changes in Atlastin isoforms


January 2 - NO WIP

January 9
Aparna Mahadevan (Kurpios Lab) - Integrated role of left-right Pitx2 pathway and Cxcl12-Cxcr4 chemotaxis in patterning functional gut lymphatics
Carl Schiltz (Chappie Lab) - Elucidating the mechanism of RexA-mediated lytic cycle induction in lambda phage

January 16 - NO WIP, Martin Luther King Holiday

January 23 - NO WIP, SPECIAL SEMINAR, Boyce Thompson Institute Auditorium

January 30
Carolyn Kelly (Sondermann Lab) - Structural and functional characterization of dynamin-related G proteins
Erin Nicklow (Sevier Lab) -Redox modification of Fes1 and its role in cellular oxidative stress response


February 6 - NO WIP, BBS Recruitment

February 13
Kristeen Pareja (Sevier Lab) - Characterization of Sil1
Arash Larifkar (Cerione Lab) - TBA

February 20 - NO WIP, February Break

February 27
Ahmad Cluntun (Cerione Lab) - TBA
Justin Lormand (Sondermann Lab) - TBA


March 6
Julio Sanchez (Cerione Lab) - TBA
Shing Hu (Kurpios Lab) - TBA

March 13
Divya Shiroor (Adler Lab) - TBA
Ed Partlow (Hollopeter Lab) - TBA

March 20
Kevin Siegenthaler (Sevier Lab)
The nucleotide exchange factor Sil1 is also a thiol-based redox regulator of the molecular chaperone BiP
Kevin Michalski (Kawate Lab)
Efforts to crystallize a pannexin-1 channel