Advancing the health and well-being of animals and people


Dr. Robert H. Wasserman


Dr. Robert H. Wasserman

College of Veterinary Medicine
Cornell University
Ithaca, NY 14853-6401
rhw2@cornell.edu

Robert H. Wasserman


Education:

B.S.  Cornell University, 1949
M.S. Michigan State University, 1951
Ph.D. Cornell University, 1953


Positions

Associate Professor, University of Tennessee, Atomic Energy Program, 1953-1955
Senior Scientist, Medical Division, Oak Ridge Institute of  Nuclear Studies, 1955-1957
Associate Professor, Physical Biology, Veterinary Medicine, 1957-1963
Professor, Physiology, Veterinary Medicine, 1963-
Chairman, Department of Physiology, Veterinary Medicine, 1983-1987
Chairman, Section of Physiology, Biological Sciences, 1983-1987
James Law Professor of Physiology, 1989-1997
James Law Professor of Physiology, Emeritus, 1997-

        
Awards:

New York State Regents Scholarship for Cornell ‑ 1943
Guggenheim Fellowship ‑ 1964‑1965
National Science Foundation Fellowship ‑ 1964‑1965
Guggenheim Fellowship ‑ 1972
Mead Johnson Award,  American  Institute of Nutrition 1969
National Academy of Sciences, 1980-
Prix Andre Lichtwitz Prize from Institut National de la Sante et de la  Researche  Medicale, Paris, France, 1982
MERIT Status by National Institutes of Health Advisory Council, 1989
William F. Neuman Award, American Society for Bone and Mineral Research, 1990
Fellow, American Institute of Nutrition, 1992
Career Recognition Award, Vitamin D Workshop, Inc., 1994


Sabbatical Activity:

Institute of Biological Chemistry,  University of Copenhagen, 1964‑1965, on a Guggenheim Fellowship
Department of Animal Physiology and Nutrition, University of Leeds, England, 1972 , on second Guggenheim Fellowship
National Institute of Aging,  National Institute of Health, Baltimore, MD, 1983


Areas of Research:

Transfer of calcium and other alkaline earths across biological membranes.
Mechanism of vitamin D action on calcium movement across intestine.
Properties and characteristics of  Vitamin D‑induced calcium‑binding proteins.
1,25‑Dihydroxycholecalciferol activity in various plants.
Biological transport of toxic metal ions.
Transport of toxic metal ions.
Calcium and phosphorus metabolism Protein sequencing and amino acid analysis.


Cornell conferences organized and published:

Transfer of Calcium and Strontium Across Biological Membranes (Academic Press, 1963)
Calcium Binding Proteins and Calcium Function (Elsevier North-Holland, 1977)


Number of published journal articles, reviews, and abstracts:     402

Selected publications                    

  1. R.H. Wasserman, C.L. Comar, M.M. Nold, and F.W. Lengemann.  Placental transfer of calcium and strontium in the rat and rabbit.  Am. J. Physiol. 189: 91‑97, 1957.
  2. R.H. Wasserman, F.W. Lengemann, and C.L. Comar.  Comparative metabolism of calcium and strontium in lactation.  J. Dairy Sci. 41: 812‑821, 1958.
  3. R.H. Wasserman, F.A. Kallfelz, and C.L. Comar.  Active transport of calcium by rat duodenum in vivo.  Science 133: 883‑884, 1961.
  4. R.H. Wasserman.  Studies on vitamin D3 and the intestinal absorption of calcium and other ions in the rachitic chick.  J. Nutr. 77: 69‑80, 1962.
  5. R.H. Wasserman, and A.N. Taylor.  Vitamin D3‑induced calcium‑binding protein in chick intestinal mucosa.  Science 152: 791‑793, 1966.
  6. F.A. Kallfelz, A.N. Taylor and R.H. Wasserman.  Vitamin D-induced calcium‑binding factor in rat intestinal mucosa.  Proc. Soc. Exptl. Biol. Med. 125: 54‑58, 1967.
  7. R.A. Corradino, and R.H. Wasserman.  Vitamin D3: Induction of calcium‑binding protein in embryonic chick intestine in vitro. Science 172: 731‑733, 1971.
  8. R.H. Wasserman and A.N. Taylor.  Intestinal absorption of phosphate in the chick: Effect of vitamin D3 and other parameters.  J. Nutr. 103: 586‑599, 1973.
  9. M. Villareale, L.V. Gould, R.H. Wasserman, A. Bar, R.T. Chiroff, and W.H.Bergstrom.  Diphenylhydantoin: Effects on calcium metabolism in the chick.  Science 183: 671‑673, 1974.
  10. R.H. Wasserman.  Calcium absorption and calcium‑binding protein synthesis: Solanum malacoxylon reverses strontium inhibition.  Science 183: 1092‑1094, 1974.
  11. P. Bredderman, and R.H. Wasserman.  Chemical composition, affinity for calcium, and some related properties of the vitamin D‑dependent calcium‑binding protein.  Biochemistry 13: 1687‑1694, 1974.
  12. R.H. Wasserman, R.A. Corradino, and L.P. Krook.  Cestrum diurnum: A domestic plant with 1,25-dihydroxycholecalciferol-like activity.  Biochem. Biophys. Res.Comm. 62: 85‑91, 1975.
  13. J.J. Feher, and R.H. Wasserman.  Evidence for a membrane‑bound form of chick intestinal calcium‑binding protein.  Fed. Proc. 35: 339, 1976 (ABST).
  14. R.H. Wasserman, J.D. Henion, M.R. Haussler, and T.A. McCain.  Evidence that a calcinogenic factor in Solanum malacoxylon is a 1,25‑dihydroxyvitamin D3‑glycoside.  Science 194: 853‑855, 1976.                                                       
  15. M.R. Hughes, T.A. McCain, S. Chang, M.R. Haussler, M. Villareale and R.H.Wasserman.  Presence of 1,25-dihydroxyvitamin D3‑glycoside in the calcinogenic plant Cestrum diurnum.  Nature 268: #5618, 347‑349, 1977.
  16. M. Peterlik, and R.H. Wasserman.  Regulation by vitamin D of intestinal phosphate absorption.  Hormone and Metabolic Research 12: 216-219,1980.
  17. C.S. Fullmer, and R.H. Wasserman.  The amino acid sequence of bovine intestinal calcium‑binding protein.  J. Biol. Chem. 256: 5669‑5674, 1981.
  18. C.S. Fullmer and R.H. Wasserman.  Chicken intestinal 28‑kilodalton calbindin‑D: Complete amino acid sequence and structural considerations.  Proc. Natl. Acad. Sci. (USA) 84: 4772‑4776, 1987.
  19. Y.‑S. Lee, A.N. Taylor, T.J. Reimers, S. Edelstein, C.S. Fullmer and R.H. Wasserman.  Calbindin‑D (CaBP) in Peripheral Nerve Cells is Vitamin D and Calcium Dependent.  Proc. Natl. Acad. Sci. USA, 84: 7344‑7348, 1987.
  20. Y.‑S. Lee, T.J. Reimers, R.G. Cowan, C.S. Fullmer and R.H. Wasserman.  Calcium‑dependent translocation of calbindin‑D28K from intestine to blood.  Arch. Biochem. Biophys. 261: #1, 27‑34, 1988.
  21. M. Weissenberg, A. Levy and R.H. Wasserman.  Distribution of calcitriol activity in Solanum Glaucophyllum plants and cell cultures.  Phytochemistry 28: 795‑798, 1989.
  22. H.M. Mykkänen and R.H. Wasserman.  Reactivity of sulfhydryl groups in the brush border membranes of chick duodena is increased by 1,25‑dihydroxycholecalciferol.  Biochim. Biophys. Acta. 1033: 282‑286, 1990.
  23. S. Chandra, C.S. Fullmer, C.A. Smith, R.H. Wasserman, and G.H. Morrison.  Ion microscopic imaging of calcium transport in the intestinal tissue of vitamin D‑deficient and vitamin D‑replete chicks: A 44Ca stable isotope study.  Proc. Natl. Acad. Sci. USA, 87: 5715‑5719, 1990.
  24. N.T.de Talamoni, H.M. Mykkänen and R.H. Wasserman.  Enhancement of sulfhydryl groups availability in the intestinal brush border membrane by deficiencies of dietary calcium and phosphorus in chicks.  J. Nutr. 120: 1198‑1204, 1990.
  25. R.H. Wasserman, C.A. Smith, C.M. Smith, M.E. Brindak, C.S. Fullmer, L. Krook, J.T. Penniston and R. Kumar.  Immunohistochemical localization of a calcium pump and calbindin-D28K in the oviduct of the laying hen.  Histochemistry 96: 413-418, 1991.
  26. R.H. Wasserman, C.A. Smith, M.E. Brindak, N. de Talamoni, C.S. Fullmer, J.T. Penniston and R. Kumar.  Vitamin D and mineral deficiencies increase the plasma membrane calcium pump of chicken intestine.  Gastroenterology, 102: 886-894, 1991.
  27. J.J. Feher, C.S. Fullmer and R.H. Wasserman.  The role of facilitated diffusion of calcium by calbindin in intestinal calcium absorption.  Am. J. Physiol. 262: C517-C526, 1992.
  28. Wasserman, R.H. Vitamin D and the dual processes of intestinal calcium absorption.  J. Nutr. 134: 3137-3139, 2004