Advancing the health and well-being of animals and people


Principal Investigator: Marjory Brooks
Co- Principal Investigator: Sally Anne Ness

Department of Population Medicine and Diagnostic Sciences
Email: mbb9@cornell.edu; Phone: 607-253-3207
Sponsor: American Holistic Veterinary Medical Foundation (AHVMF)
Grant Number: N/A
Title: Investigating the Procoagulant Properties of Yunnan Baiyao in Horses
Annual Direct Cost: $24,203
Project Period: 09/01/13-08/31/14

Description (provided by applicant): Blood loss is a serious, and potentially fatal complication of trauma, surgery, and critical illness in horses. There are currently few medications proven effective for treating or preventing hemorrhage, and consequently, many horses suffer from uncontrolled blood loss. Yunnan Baiyao is a traditional Chinese herbal remedy for bleeding that has come into recent use in veterinary medicine. In horses, Yunnan Baiyao has been given to broodmares for post-foaling hemorrhage, to minimize bleeding from traumatic injuries, and for pulmonary hemorrhage in racehorses. Despite its use in veterinary and human practice, the mechanism of action of Yunnan Baiyao remains unknown, and there is currently little scientific information to guide therapy.

The purpose of this study is to bridge this current gap in knowledge by discovering how Yunnan Baiyao affects equine blood clotting. We will administer Yunnan Baiyao to healthy adult horses and then measure the function of their platelets (a key component of coagulation), as well as their ability to form and breakdown blood clots. At the conclusion of the study, we will have determined if and how Yunnan Baiyao promotes coagulation in horses and have an improved understanding of its potential uses in clinical veterinary medicine.