Department of Clinical Sciences and Department of Biomedical Sciences
Contact Information: Email: email@example.com, Phone: 607-253-3817
Sponsor: Cornell University Center for Advanced Technology
Grant Number: N/A
Title: Variation Discovery Towards Fine-Mapping Dog Disease Traits
Annual Direct Cost: $48,390
Project Period: 07/01/2012-06/30/2013
DESCRIPTION (provided by applicant): The investigators propose to accelerate fine-mapping and identification of causal mutations for four traits (portosystemic vascular anomalies, owner-directed aggression, orthopedic traits and lymphoma) by whole genome sequencing, one affected and one unaffected dog for each trait (eight dogs total). Discovery of new sequence variations at loci associated with the traits will enable follow-up mutation detection and deliver trait-associated variants that will be included in a future improved canine genotyping array.