Vitamin D not only plays an important role in regulating calcium in the body, but it also promotes a healthy immune system. We currently do not know if dogs with autoimmune disease have low levels of vitamin D, and if so what role that may play in promoting autoimmunity. Low vitamin D levels have been associated with autoimmune disease in rodent models and people. This study seeks to determine blood levels of vitamin D in dogs with immune mediated disease compared to healthy dogs. Markers of immune function will also be assessed. Vitamin D levels will then be compared to patient outcomes to determine if dogs with lower vitamin D levels have poorer prognoses.
ELIGIBILITY: Any dog with suspected immune mediated disease can be enrolled initially in the study. Dogs with concurrent disease or determined to have secondary immune mediated disease will be excluded. Healthy dogs will be enrolled as controls.
COMPENSATION: All routine diagnostic tests will be the responsibility of the client.
OWNER RESPONSIBILITY: Patients enrolled in the study may be contacted for up to two years to determine outcomes. No recheck visits in person will be necessary.