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Influenza viruses in horses and transfer to dogs

One model system that we are examining is the emergence of the canine influenza virus (CIV) in dogs after transfer of the H3N8 equine influenza virus to greyhounds around 2000. Those studies are examining the evolution of the virus in dogs to determine how the virus has changed during the 14 years of continuous passage in dogs. We are also examining the host barriers to infection that normally prevent the infection of dogs by influenza viruses. The viruses in dogs are confined to only a small number of large animal shelters, and they appear not to be able to spread readily into more dispersed populations of dogs.