Biological and Biomedical Sciences Graduate Program

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Medical Genetics & Genomics

Many diseases have a genetic basis with either simple (one gene) or complex (many genes) inheritance. Breeds of companion, domestic or lab animals often have genetic predisposition to diseases as an inadvertent consequence of inbreeding. Researchers at Cornell are using modern genomic technologies to pinpoint genetic variants that underlie a variety of breed-specific diseases of animals, such as cancers and heart diseases of dogs, immune diseases in horses, and reproductive disorders in mice. Ultimately, our researchers hope to use the genetic discoveries for early intervention, stem cell treatment, selective breeding, and application to human disease.

Faculty Research area Graduate Field Membership (Follow links to the Biological & Biomedical Sciences Fields)
angert
Esther Angert
Comparative genomics of bacterial developmental systems, genomic analysis of symbiotic microbes, molecular evolution Genomics
Doug Antcazk
Doug Antczak
pregnancy immunology; immunogenetics; equine immunology Comparative Biomedical Sciences;
Immunology & Infectious Disease; Genomics; Molecular & Integrative Physiology
Kathryn Boor
Kathryn Boor
bacterial responses to environmental challenges; food microbiology; food safety; differentiation and characterization of virulence determinants in E. coli 0157: H7 and Listeria monocytogenes Microbiology;
Environmental Toxicology;
Food Science & Technology
Boyko
Dr. Adam Boyko
genomic investigation of dogs as a model of genetic disease and evolutionary genetics Comparative Biomedical Sciences; Computational Biology; Genomics; Molecular & Integrative Physiology
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Nicolas Buchon
Host/Microbe relationships and Control of intestinal stem cell behavior in homeostasis and disease Comparative Biomedical Sciences;
Entolmology;
Genetics, Genomics & Development
Sharon A. Center
Sharon A. Center
liver and kidney diseases of small animals Comparative Biomedical Sciences
Yung-Fu Chang
Yung-Fu Chang
mechanisms of infection, particularly leptospira and salmonella Comparative Biomedical Sciences;
Zoology & Wildlife Conservation
Ruth Collins
Ruth Collins
pharmacology; cancer cell biology; small GTPase regulation of intracellular traffic and cellular growth control Comparative Biomedical Sciences;
Microbiology;
Pharmacology
;
Biochemistry, Molecular & Cell Biology;
Genomics;
Neurobiology & Behavior
Scott Coonrod
Scott Coonrod
reproductive physiology; molecular and cellular physiology; epigenetic reprogramming during the egg-to-embryo transition; mechanisms by which specific histone modifications are dynamically regulated during hormone-dependent gene transcription in breast cancer cells Comparative Biomedical Sciences;
Molecular & Integrative Physiology
Matthew DeLisa
Matthew DeLisa
molecular biotechnology; protein biogenesis and folding pathways; protein engineering Comparative Biomedical Sciences;
Microbiology;
Biomedical Engineering;
Chemical Engineering
Maria Julia Bevilaqua Felippe
Maria Julia Bevilaqua Felippe
cellular and molecular mechanisms involved in B-cell response; neonatal immunology and response to vaccination; immunomodulation using biologic response modifiers; cancer immunotherapy; characterization of primary and secondary immunodeficiencies Comparative Biomedical Sciences;
Immunology & Infectious Disease
Maria Garcia-Garcia
Maria Garcia-Garcia
developmental biology in mice and flies; genetics of developmental mechanisms that influence embryonic morphology Comparative Biomedical Sciences;
Molecular & Integrative Physiology;
Biochemistry, Molecular & Cell Biology;
Genetics, Genomics and Development
Michael I. Kotlikoff
Michael I. Kotlikoff
muscle biology; mouse genetics; molecular imaging; ion channels; physiological genomics; cellular signaling; genetic cell sensors; conditional gene targeting Comparative Biomedical Sciences;
Molecular & Integrative Physiology;
Pharmacology;
Biophysics;
Genomics;
Neurobiology & Behavior
Natasza Kurpios
Natasza Kurpios
tissue morphogenesis; cell shape and architecture; organ development; gut morphogenesis; mammary gland biology; breast cancer Molecular & Integrative Physiology;
Pharmacology;
Genetics, Genomics and Development
lazzaro
Brian Lazzaro
  Comparative Biomedical Sciences
Siu Syliva Lee
Siu Sylvia Lee
molecular genetics of aging; signaling pathways of nutrient sensing; molecular basis of stress response Comparative Biomedical Sciences; Biochemistry, Molecular & Cell Biology;
Computational Biology;
Genetics, Genomics and Development;
Nutrition
libert
Sergiy Libert
Mice; molecular biology of aging, age-associated diseases, cancer, neurodegeneration; anorexia, energy metabolism,

Comparative Biomedical Sciences;                  Molecular & Integrative Physiology

David Lin
David Lin
axon guidance and target selection during development of mouse olfactory systems using genetics in vitro and genomic approaches; developmental biology; olfaction; axon guidance Comparative Biomedical Sciences;
Molecular & Integrative Physiology;
Pharmacology;
Biochemistry, Molecular & Cell Biology;
Genetics, Genomics and Development;
Genomics; Neurobiology & Behavior
locasale
Jason Locasale
Cancer metabolism; systems pharmacology; computational biology; metabolomics; cancer genomics Pharmacology
Vicki Meyers-Wallen
Vicki Meyers-Wallen
inherited canine diseases; reproductive tract disorders Comparative Biomedical Sciences;
Molecular & Integrative Physiology
N. Sydney Moise
N. Sydney Moise
arrhythmias; Sudden Death Syndrome; cardiology Comparative Biomedical Sciences
Alexander Nikitin
Alexander Nikitin
genetic modeling of human cancer in the mouse; early detection and monitoring of carcinogenesis; neoplasms of reproductive and endocrine systems Comparative Biomedical Sciences;
Molecular & Integrative Physiology;
Environmental Toxicology
Kimberly O'Brien
Kimberly O'Brien
calcium metabolism and bone health; control of maternal/fetal nutrient; partitioning and cellular mineral transport; micronutrient status in international settings; development of mass spectrometric methodology; pediatric bone health; pregnancy and mineral metabolism in adolescents Molecular & Integrative Physiology;
Nutrition
Ling Qi
Ling Qi
transcriptional control of metabolic syndrome; unfolded protein response; obesity and diabetes Molecular & Integrative Physiology;
Biochemistry, Molecular & Cell Biology;
Genetics, Genomics and Development;
Nutrition
John Schimenti
John Schimenti
mouse genetics and functional genomics; genomic instability; genetic recombination; genetics of gametogenesis and development; use of ES cells to mutagenize the mouse genome Comparative Biomedical Sciences;
Molecular & Integrative Physiology;
Biochemistry, Molecular & Cell Biology;
Genetics, Genomics and Development;
Genomics
Kenneth W. Simpson
Kenneth W. Simpson
gastroenterology Comparative Biomedical Sciences
Soloway
Paul Soloway
Epigenetic regulatory mechanisms in mammals Comparative Biomedical Sciences;
Genomics
;
Biochemistry, Molecular & Cell Biology;
Genetics, Genomics and Development;
Nutrition
Michael Stanhope
Michael Stanhope
molecular evolution and comparative genomics of infectious disease organisms Comparative Biomedical Sciences; Genomics
Nathan Sutter
Nathan Sutter
genetic regulation of growth in the canine; identification of genes related to risk of specific cancers in particular canine breeds; study of genes that contribute to body size in the dog Zoology & Wildlife Conservation; Genetics, Genomics and Development
Rory J. Todhunter
Rory J. Todhunter
canine hip dysplasia; genetic linkage analysis; osteoarthritis Comparative Biomedical Sciences
Gary R. Whittaker
Gary R. Whittaker

Pathogenesis of influenza viruses, corona viruses and arena viruses. Host range and receptors, activation of membrane fusion, macrophage- and neurotropism, anti-viral therapeutics, diagnostic tests, virus-bacteria co-infections

Comparative Biomedical Sciences; Immunology & Infectious Disease; Microbiology; Pharmacology; Biochemistry, Molecular & Cell Biology
Mariana Wolfner
Mariana Wolfner
molecular, developmental, and genetic studies of Drosophila reproduction; embryogenesis and nuclear envelope; function and evolution of reproductive genes Biochemistry, Molecular & Cell Biology;
Ecology & Evolutionary Biology;
Genetics, Genomics and Development
Andrew Yen
Andrew Yen
leukemia; cell growth and differentiation; oncogenes/genetics Comparative Biomedical Sciences; Environmental Toxicology